结缔组织病引起的重症多形红斑1例  

1 Case of Stevens-Johnson Syndrome Caused by Connective Tissue Disease

作　　者：马祖超 

机构地区：[1]成都中医药大学临床医学院,四川 成都

出　　处：《临床医学进展》2023年第12期19929-19933,共5页Advances in Clinical Medicine

摘　　要：目的:通过病例回顾,提高对重症多形红斑的病因、临床表现、系统治疗的认识。方法:总结1例重症多形红斑患者的临床资料,并复习相关文献资料。结果:本例患者临床表现为全身泛发红斑丘疹,呈虹膜样改变,伴电解质紊乱及肾功能损害,完善相关检查,排除药物、感染、接触物及其他内脏疾病后,考虑为自身结缔组织病引起本病的发生。予糖皮质激素、大剂量丙种球蛋白、益赛普等联合治疗后成功治愈,同时缩短了疗程。结论:重症多形红斑的病因复杂,临床上应注意排查,经系统治疗后能及时阻止疾病的进展,缓解病情。Objective: To improve the understanding of the etiology, clinical manifestations and systematic treatment of Stevens-Johnson syndrome through case review. Methods: The clinical data of a case of Stevens-Johnson syndrome were summarized and relevant documents were reviewed. Results: The patient showed generalized erythematous papules, iris-like changes, electrolyte disorder and renal function damage. After excluding drugs, infections, contacts and other visceral diseases, the patient was considered to cause the connective tissue disease. The combination treatment of glucocorti-coids, high-dose gamma globulin and etanercept was successfully cured, and the course of treat-ment was shortened. Conclusion: The etiology of Stevens-Johnson syndrome is complex, and clinical attention should be paid to investigation. After systematic treatment, the progression of the disease can be prevented in time to relieve the disease.

关 键 词：重症多形红斑 结缔组织病 甲泼尼龙 丙种球蛋白 益赛普 

分 类 号：R75[医药卫生—皮肤病学与性病学]