儿童系统性红斑狼疮呼吸系统受累研究进展  

Research Progress of Respiratory Involvement in Children with Systemic Lupus Erythematosus

作　　者：瞿宁 朱洪涛[1] 

机构地区：[1]新疆医科大学第一附属医院儿内三科,新疆 乌鲁木齐

出　　处：《临床医学进展》2023年第12期20128-20136,共9页Advances in Clinical Medicine

摘　　要：呼吸系统受累是儿童系统性红斑狼疮常见的并发症之一,严重影响系统性红斑狼疮患儿的预后。在疾病发展过程中,高达50%的系统性红斑狼疮患儿可能发生呼吸系统受累,根据影响的部位,儿童系统性红斑狼疮呼吸系统受累可以表现为:胸膜、肺实质、支气管和细支气管、肺血管、呼吸肌等。综合运用血清学检测、肺部及心脏影像学,有助于尽快明确诊断。本综述描述了儿童系统性红斑狼疮呼吸系统受累的发病机制、病变类型以及相关治疗方案,旨在提高临床医师对儿童系统性红斑狼疮呼吸系统受累的认识。Respiratory system involvement is one of the common complications of systemic lupus erythema-tosus in children, which seriously affects the prognosis of children with systemic lupus erythema-tosus. In the course of disease development, up to 50 % of children with systemic lupus erythema-tosus may be involved in the respiratory system. According to the affected site, respiratory system involvement in children with systemic lupus erythematosus can be manifested as: pleura, lung pa-renchyma, bronchus and bronchioles, pulmonary vessels, respiratory muscles, etc. The comprehen-sive use of serological detection, lung and cardiac imaging is helpful to make a definite diagnosis as soon as possible. This review describes the pathogenesis, lesion types and related treatment op-tions of respiratory system involvement in children with systemic lupus erythematosus, aiming to improve clinicians’ understanding of respiratory system involvement in children with systemic lu-pus erythematosus.

关 键 词：儿童 系统性红斑狼疮 呼吸系统 综述 

分 类 号：R59[医药卫生—内科学]