代谢健康型肥胖与炎症因子的研究进展  

Research Progress of Metabolically Healthy Obesity and Inflammatory Factors

作　　者：许虎彪 张颖[1] 

机构地区：[1]新疆医科大学第一附属医院干部保健中心综合内二科,新疆 乌鲁木齐

出　　处：《临床医学进展》2024年第1期546-551,共6页Advances in Clinical Medicine

摘　　要：肥胖所导致的慢性持续性低度炎症是胰岛素抵抗、2型糖尿病、心血管疾病发生发展的重要危险因素,然而有些肥胖个体表现出较好的新陈代谢特征,这种肥胖亚型被描述为“代谢健康肥胖”(MHO)。研究表明脂肪组织的慢性炎症可能是决定肥胖者代谢是否正常的关键性因素,MHO的生物学机制目前尚不明确,但可能与其有利的脂肪因子分泌模式有关。故本文就MHO与炎症因子的关系作一综述。The chronic and persistent low-grade inflammation caused by obesity is an important risk factor for the development of insulin resistance, type 2 diabetes, and cardiovascular disease. However, some obese individuals show better metabolic characteristics, and this subtype of obesity is described as “metabolically healthy obesity” (MHO). Studies have shown that chronic inflammation of adipose tissue may be a key factor in determining whether obese people have a normal metabolism. The bi-ological mechanism of MHO is still unclear, but it may be related to its favorable adipokine secretion pattern. Therefore, this article reviews the relationship between MHO and inflammatory factors.

关 键 词：肥胖 代谢健康型肥胖 炎症因子 

分 类 号：R58[医药卫生—内分泌]