TG/HDL比值与2型糖尿病周围神经病变的相关性  

Association of TG/HDL Ratio with Peripheral Neuropathy in Type 2 Diabetes Mellitus

作　　者：木拉迪力江·努尔合买提 米娜瓦尔·胡加艾合买提[1] 

机构地区：[1]新疆医科大学第一附属医院全科医学科,新疆 乌鲁木齐

出　　处：《临床医学进展》2024年第1期1252-1257,共6页Advances in Clinical Medicine

摘　　要：糖尿病周围神经病(DPN)是糖尿病患者最常见的慢性并发症。目前2型糖尿病周围神经病发病机制尚未完全清楚,是由多种因素综合作用的结果。其中脂代谢异常在糖尿病进展过程中扮演者重要角色,TG (三酰甘油)是心血管疾病的独立危险因素,HDL具有抗氧化和抗炎症的能力,与单个的血脂指标相比,一些常见血脂比值(TG/高密度脂蛋白(HDL)比值、lg (TG/HDL-C)等)在胰岛素抵抗、糖尿病发病率、代谢综合征、评估β细胞功能、糖尿病大血管及微血管并发症等方面具有临床指导意义。Diabetic peripheral neuropathy (DPN) is the most common chronic complication in diabetic pa-tients. At present, the pathogenesis of peripheral neuropathy in type 2 diabetes is not fully under-stood, and it is the result of a variety of factors. Abnormal lipid metabolism plays an important role in the progression of diabetes. TG (triacylglycerol) is an independent risk factor for cardiovascular diseases, and HDL has antioxidant and anti-inflammatory capabilities. Compared with a single lipid index, some common lipid ratios (TG/high-density lipoprotein (HDL) ratio, lg (TG/HDL-C), etc.) have clinical significance in insulin resistance, diabetes incidence, metabolic syndrome, assessment of β cell function, and diabetes macrovascular and microvascular complications.

关 键 词：三酰甘油/高密度脂蛋白胆固醇 2型糖尿病 糖尿病周围神经病变 

分 类 号：R58[医药卫生—内分泌]