急性冠脉综合征相关急性肾损伤临床研究进展  

Advances in Clinical Research on Acute Kidney Injury Associated with Acute Coronary Syndromes

作　　者：王润泽 李素华[1,2,3] 

机构地区：[1]新疆医科大学第一附属医院肾脏疾病中心,省部共建中亚高发病成因与防治国家重点实验室, 新疆 乌鲁木齐 [2]新疆维吾尔自治区肾脏病研究所,新疆 乌鲁木齐 [3]新疆肾脏替代治疗临床医学研究中心,新疆 乌鲁木齐

出　　处：《临床医学进展》2024年第2期2994-3003,共10页Advances in Clinical Medicine

摘　　要：急性肾损伤(Acute kidney injury, AKI)为各种原因所致的短期内肾功能迅速减退,主要表现为肾小球滤过率(GFR)下降,伴有如尿素、肌酐等氮质产物在体内蓄积,水、电解质及酸碱平衡紊乱的临床综合征。同时也是心血管疾病干预治疗后出现的主要不良事件之一。急性冠脉综合征(Acute coronary syndrome, ACS)作为冠心病主要分类之一,也是急诊急危重症之一,本综述在急性冠脉综合征患者治疗后急性肾损伤的发病机制、危险因素等方面加以论述,以期为急性冠脉综合征患者预防AKI提供指导。Acute kidney injury (AKI) is a clinical syndrome in which kidney function declines rapidly in the short term due to a variety of causes, manifesting mainly as a decrease in glomerular filtration rate (GFR), accompanied by accumulation of nitrogen products such as urea and creatinine in the body, and disturbances in water, electrolytes and acid-base balance. It is also one of the most common adverse events following cardiovascular interventions. As one of the main categories of coronary artery disease and one of the acute and critical emergency conditions, this review discusses the pathogenesis and risk factors of post-treatment acute kidney injury in patients with acute coronary syndrome to provide guidance for the prevention of AKI in patients with acute coronary syndrome.

关 键 词：急性冠脉综合征 急性肾损伤 危险因素 

分 类 号：R54[医药卫生—心血管疾病]