亚低温治疗对于HIE患儿生理的影响  

Effects of Subcooling Therapy on the Physiology of Children with HIE

作　　者：周润泽 韦红[1] 

机构地区：[1]重庆医科大学附属儿童医院新生儿科,国家儿童健康与疾病临床医学研究中心,儿童发育疾病研究教育部重点实验室,儿科学重庆市重点实验室,重庆

出　　处：《临床医学进展》2024年第2期3789-3793,共5页Advances in Clinical Medicine

摘　　要：亚低温治疗作为改善新生儿缺氧缺血性脑病预后的治疗手段可能会对患儿的生理功能造成一定的影响,由于缺氧缺血性脑病容易合并多器官功能衰竭因此更需要紧密检测亚低温治疗期间的各项指标。亚低温治疗会造成一过性血小板减少和窦性心动过缓,其他机体影响并不明显,甚至可能对于心肾功还有一定保护作用。其次还需警惕亚低温治疗过程中的药动学,亚低温可能会延缓镇静剂的代谢过程。Hypothermia as a therapeutic tool to improve the prognosis of neonatal hypoxic-ischemic encepha-lopathy may have a certain impact on the physiological function of the children, as hypoxic- ischem-ic encephalopathy is prone to combined multi-organ dysfunction syndrome, so it is more important to closely monitor the indicators of the period of hypothermia treatment. Therapeutic hypothermia will cause transient thrombocytopenia and sinus bradycardia, other body effects are not obvious, and may even have a certain protective effect on cardiac and renal function. Secondly, we should al-so be alert to the pharmacokinetics of hypothermia;hypothermia may slow down the metabolism of sedatives.

关 键 词：缺氧缺血性脑病 亚低温 生理 多器官功能衰竭 

分 类 号：R72[医药卫生—儿科]