炎性衰老在老年衰弱综合征中的发生机制  

The Mechanism of Inflamm-Aging in Elderly Frailty Syndrome

作　　者：米叶赛·艾尼瓦尔 王红[2] 

机构地区：[1]新疆医科大学第一附属医院,新疆 乌鲁木齐 [2]新疆医科大学第一附属医院综合内二科,新疆 乌鲁木齐

出　　处：《临床医学进展》2024年第3期1487-1492,共6页Advances in Clinical Medicine

摘　　要：衰弱是一种与增龄相关的老年综合征,增加老年人不良健康结局的风险,减少预期寿命。炎性衰老(inflamm-aging)是机体在衰老过程中所显现出的慢性促炎症反应状态,并随着衰老而进行性加剧。研究表明,炎性衰老可能是导致衰弱的重要原因。本文对炎性衰老和老年人衰弱综合征的机制进行综述,为衰弱的早期诊断和干预提供理论依据。Frailty is a geriatric syndrome associated with increasing age, increasing the risk of adverse health outcomes and decreasing life expectancy in older adults. Inflamm-aging is a chronic pro-inflammatory response state of the body that manifests itself during the aging process and progressively intensifies with aging. Research suggests that inflamm-aging may be an important cause of frailty. In this paper, we review the mechanisms of inflamm-aging and debilitating syndromes in the elderly to provide a theoretical basis for early diagnosis and intervention of frailty.

关 键 词：衰弱 炎性衰老 机制 

分 类 号：R47[医药卫生—护理学]