慢性阻塞性肺疾病合并肺栓塞的临床进展  

Clinical Progress of Chronic Obstructive Pulmonary Disease Complicated with Pulmonary Embolism

作　　者：熊玉林 李英兰[2] 

机构地区：[1]青海大学医学院,青海 西宁 [2]青海省人民医院全科医学,青海 西宁

出　　处：《临床医学进展》2024年第4期768-777,共10页Advances in Clinical Medicine

摘　　要：慢性阻塞性肺疾病(COPD)是一种常见的、可预防和可治疗的疾病,中国慢阻肺的发病率每年都在增长,成为一个巨大且不断增长的公共卫生负担。多因素分析显示,COPD是肺栓塞(PE)发生的独立危险因素之一,COPD患者肺栓塞的发生率明显高于正常人。由于相同的临床症状,在COPD急性加重中,PE很容易被忽视,从而延误患者治疗,影响预后。慢阻肺合并肺栓塞的诊断仍是一项挑战,因此对于早期识别、积极寻找有效的评估方法、及时诊治尤为重要。本文对慢阻肺合并肺栓塞患者的相关机制、危险因素、生物学标志物研究进展进行阐述。Chronic obstructive pulmonary disease (COPD) is a common, preventable and treatable disease, and the incidence of COPD in China is increasing every year, becoming a large and growing public health burden. Multifactor analysis showed that COPD was one of the independent risk factors for pulmonary embolism (PE), and the incidence of PE in COPD patients was significantly higher than that in normal people. Due to the same clinical symptoms, PE is easily overlooked in acute exacerbations of COPD, thus delaying patient treatment and affecting prognosis. The diagnosis of COPD combined with pulmonary embolism is still a challenge, so it is particularly important for early identification, active search for effective evaluation methods, and timely diagnosis and treatment. In this paper, we reviewed the research progress on the mechanism, risk factors and biological markers of COPD patients with pulmonary embolism.

关 键 词：慢性阻塞性肺疾病 肺栓塞 生物学标志物 

分 类 号：R56[医药卫生—呼吸系统]