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机构地区:[1]重庆医科大学附属第二医院呼吸与危重症医学科,重庆 [2]重庆市南岸区第三人民医院内一科,重庆 [3]重庆市急救医疗中心(重庆大学附属中心医院)消化内科,重庆 [4]重庆医科大学附属第二医院精准医学中心,重庆
出 处:《临床医学进展》2024年第5期1079-1087,共9页Advances in Clinical Medicine
摘 要:脓毒血症被定义为由于宿主对感染的反应失调而导致的危及生命的器官功能障碍,作为脓毒症的严重亚型,脓毒性休克是指脓毒症并发了严重的循环、细胞和代谢异常,其死亡率显著增加,是重症监护单元患者管理的重点及难点。本文作者检索了近5年关于脓毒性休克治疗的文献,从脓毒性休克药物和非药物治疗手段的新进展两方面进行全面综述,旨在为临床中脓毒性休克治疗提供新的循证依据。Sepsis is defined as life-threatening organ dysfunction due to dysregulation of the host response to infection. As a severe subtype of sepsis, septic shock is sepsis complicated by severe circulatory, cellular, and metabolic abnormalities, which is associated with a significant increase in mortality, and is a major focus and difficulty in the management of patients in intensive care units. In this review, the authors searched the literature on the treatment of septic shock in the last 5 years and conducted a comprehensive review in terms of new advances in both pharmacologic and nonpharmacologic therapeutic means for septic shock, aiming to provide a new evidence-based basis for the treatment of septic shock in the clinic.
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