银屑病的治疗进展  

Advances in the Treatment of Psoriasis

作　　者：赫群 张晓冬[1] 王峻嵩 沈佳丽 

机构地区：[1]北华大学附属医院皮肤科,吉林 吉林 [2]牡丹江医学院附属红旗医院重症科,黑龙江 牡丹江 [3]汕头市职业病防治所,广东 汕头

出　　处：《临床医学进展》2024年第6期575-587,共13页Advances in Clinical Medicine

摘　　要：银屑病是一种慢性、复发性的免疫介导性皮肤疾病,特征是皮肤上出现红色、鳞屑状的斑块,伴或不伴有瘙痒、干燥和脱屑,常影响头皮、肘部、膝盖等部位。银屑病的发病机制涉及多基因变异和T细胞介导的免疫反应,其诱因多样,病情容易反复。目前治疗主要为对症治疗,以缓解症状、减少发作频率,并改善患者生活质量为目标。治疗方法包括局部外用药物、系统治疗、光疗和中医疗法,以及新兴的生物制剂疗法。本文概述了这些治疗手段的应用与效果。Psoriasis is a chronic, recurrent, immune-mediated dermatological condition characterized by the appearance of red, scaly patches on the skin, which may or may not be accompanied by itching, dryness, and flaking. Commonly affecting the scalp, elbows, and knees, the pathogenesis of psoriasis involves multigenic variations and T-cell-mediated immune responses, with diverse triggers that can lead to relapses. Current treatments primarily focus on symptomatic relief, reducing the frequency of flare-ups, and enhancing the quality of life of patients. Treatment modalities include topical medications, systemic therapies, phototherapy, traditional Chinese medicine, and emerging biologic treatments. This article provides an overview of these therapeutic approaches and their effectiveness.

关 键 词：银屑病 局部外用药物 系统治疗 光疗法 生物制剂 中医治疗 

分 类 号：R75[医药卫生—皮肤病学与性病学]