髋关节术后异位骨化的研究进展  

Research Progress of Ectopic Ossification after Hip Joint Operation

作　　者：饶康 李长红[2] 

机构地区：[1]延安大学医学院,陕西 延安 [2]延安大学附属医院创伤骨科,陕西 延安

出　　处：《临床医学进展》2024年第7期427-434,共8页Advances in Clinical Medicine

摘　　要：异位骨化(Heterotopic Ossification, HO)是指在正常情况下没有骨组织的软组织内,出现了成骨细胞,并形成了骨组织。HO是髋关节骨折术后常见的并发症之一,一旦发生可能会引起较严重的后果,且由于髋关节骨折术后HO的高发病率及其发病机制的复杂性,其预防与治疗一直受到人们的关注。但学术界目前对HO发病机制的认识、最有效的预防方案、手术时机的选择、物理治疗的必要性以及基因靶向治疗的临床应用等问题尚不明确。本文通过对HO最新研究的文献进行系统评价,为髋部骨折术后HO的发病机制的研究与治疗提出专业意见。Heterotopic Ossification (HO) is the emergence of osteoblasts and the formation of bone tissue in soft tissues that normally do not have bone tissue. HO is one of the common complications after hip fracture, which may cause serious consequences once it occurs. Due to the high incidence and complexity of the pathogenesis of HO after hip fracture, its prevention and treatment have been concerned by people. However, the understanding of the pathogenesis of HO, the most effective preventive program, the selection of surgical timing, the necessity of physical therapy and the clinical application of gene targeted therapy are still unclear. Through a systematic review of the latest literature on HO, this paper provides professional suggestions for the study and treatment of the pathogenesis of HO after hip fracture.

关 键 词：异位骨化 髋关节术后 危险因素 预防 治疗 

分 类 号：R68[医药卫生—骨科学]