腹型肥胖与临床不同动脉硬化指标间的相关性研究  

The Correlation Analysis of Abdominal Obesity and Different Clinical Arteriosclerosis Indexes

作　　者：黄江明 邓蕾 吴朝晖[1] 李雁卓 李秋月 徐琳 谢振宏[1] 

机构地区：[1]武警广东总队医院心血管内科,广东 广州 [2]广东省第二人民医院民航院区体检科,广东 广州 [3]南部战区总医院心血管内科,广东 广州

出　　处：《临床医学进展》2024年第8期1038-1044,共7页Advances in Clinical Medicine

摘　　要：目的:探讨在轻中度原发性高血压患者中腹型肥胖与临床不同动脉硬化指标之间的相关性。方法:以209例轻中度原发性高血压患者为研究对象,按腹围分组,分析一般临床数据、血生化指标和各动脉硬化指标在腹围正常组与腹型肥胖组之间的差异,及腹围与各个临床动脉硬化指标之间的相关性,最后用逐步回归分析动脉硬化的独立危险因素。结果:腹型肥胖组体质指数(BMI)、甘油三酯、血清尿酸、肱踝脉搏波传导速度(baPWV)和颈动脉内膜中层厚度均显著高于腹围正常组(P Objective: To explore the correlation between abdominal obesity and different clinical arteriosclerosis indexes in patients with mild to moderate essential hypertension. Methods: 209 patients with mild to moderate essential hypertension were divided into different groups according to the abdominal circumference. The differences of general clinical data, blood biochemical indexes and arteriosclerosis indexes between the normal and increased abdominal circumference groups were analyzed, and the correlation between abdominal circumference and each clinical arteriosclerosis index was analyzed. Finally, the independent risk factors of arteriosclerosis were analyzed by stepwise regression. Result: The body mass index (BMI), triglyceride, serum uric acid, brachial-ankle pulse wave velocity (baPWV) and carotid intima-media thickness in the abdominal obesity group were significantly higher than those in the group with normal abdominal circumference (P < 0.05). Ankle brachial index (ABI), carotid plaque and other indexes had no statistical difference between the two groups. At the same time, Pearson correlation analysis showed that there was a positive correlation between abdominal circumference and baPWV, end diastolic interventricular septal thickness and carotid intima-media thickness. The correlation was the highest with baPWV and the lowest with end diastolic ventricular septal thickness. Stepwise regression analysis sh

关 键 词：轻中度高血压 腹围 动脉硬化 靶器官损害 

分 类 号：R54[医药卫生—心血管疾病]