不同病因甲状腺毒症血常规炎性细胞相关性分析研究  

Study on the Correlation Analysis of Blood Routine Inflammatory Cells in Different Causes of Thyrotoxicosis

作　　者：毛恩雯 王常英 李丽 毛军 

机构地区：[1]同济大学附属东方医院胶州医院内分泌科,山东 青岛

出　　处：《临床医学进展》2024年第8期1480-1486,共7页Advances in Clinical Medicine

摘　　要：目的:观察分析血常规炎性细胞等相关指标与甲状腺毒症不同病因的相关性,并探讨其在临床中的意义。方法:选取2022年1月至2022年12月于同济大学附属东方医院胶州医院内分泌科门诊就诊的患者49例,包括27例Graves病患者(GD组)、22例桥本甲状腺炎患者(HT组)、以及在本院体检中心健康体检的志愿者30名(CON组),比较三组间白细胞(WBC)、中性粒细胞(NC)、淋巴细胞(LC)、单核细胞(MC)、中性粒/淋巴细胞比值(NLR)、单核/淋巴细胞比值(MLR)等实验室资料及相关资料的差异。相关性分析甲状腺毒症不同病因与实验室检查指标的相关性。结果:HT组与CON组相比,WBC、LC、MLR均呈负相关(p Objective: To observe and analyze the correlation between blood routine inflammatory cells and different causes of thyrotoxicosis, and to explore its clinical significance. Methods: A total of 49 patients were selected from the endocrinology outpatient department of Jiaozhou Hospital, East Hospital Affiliated to Tongji University from January 2022 to December 2022, including 27 patients with Graves’ disease (GD group), 22 patients with Hashimoto thyroiditis (HT group), and 30 volunteers (CON group) who underwent physical examination in the physical examination center of our hospital. The laboratory data of leukocyte (WBC), neutrophil (NC), lymphocyte (LC), monocyte (MC), neutrophil/lymphocyte ratio (NLR), monocyte/lymphocyte ratio (MLR) and other relevant data were compared between the three groups. The correlation between different etiology of thyrotoxicosis and laboratory test indexes was analyzed. Results: Compared with CON group, WBC, LC and MLR in HT group were negatively correlated (p < 0.05), while there was no correlation between NC and NLR groups. Compared with CON group, NC, MC, NLR, MLR, FT3, FT4, TSH and TRAB in GD group were all negatively correlated (p < 0.05), while no correlation was found between LC and WBC groups. Compared with GD group, WBC, LC, NC, MC, FT3, FT4, TS

关 键 词：甲状腺毒症 炎性细胞 外周血白细胞计数 中性粒/淋巴细胞比值 

分 类 号：R58[医药卫生—内分泌]