参曲健脾颗粒治疗AECOPD合并营养不良的临床研究  

Clinical Study of Shenqu Jianpi Granule Treating AECOPD Complicated with Malnutrition

作　　者：谭国婷 龙玉明 李冬梅[1] 周丽[1] 邓晓琴[1] 

机构地区：[1]内江市中医医院心肺病科,四川 内江 [2]内江市第一人民医院肿瘤科,四川 内江

出　　处：《临床医学进展》2024年第9期887-893,共7页Advances in Clinical Medicine

摘　　要：目的:观察参曲健脾颗粒治疗慢性阻塞性肺疾病急性加重期(acute exacerbation of chronic obstructive pulmonary disease, AECOPD)合并营养不良患者的临床疗效。方法:选取2023年10月至2024年2月收治的112例符合纳入标准的AECOPD合并营养不良患者。采用随机数字表法随机分为观察组和对照组各56例。对照组为标准西医治疗,观察组为标准西医治疗联合参曲健脾颗粒治疗,总周期为2周。观察和比较两组患者治疗前后肺功能、血气分析指标以及CAT评分、ALB、BMI的变化,评估中医证候积分情况,并比较两组患者的临床疗效。结果:观察组在临床总有效率方面明显优于对照组(P 1)、FEV1占预计值的百分比(FEV1%pred)均有所升高,同时动脉氧分压(PaO2)、动脉二氧化碳分压(PaCO2)、CAT评分、血清白蛋白(albumin, ALB)、体重指数(body mass index, BMI)也有所改善,观察组的改善程度显著高于对照组(P Objective: To observe the clinical therapeutic effect of Shenqu Jianpi Granule in treating acute exacerbation of chronic obstructive pulmonary disease (AECOPD) complicated with malnutrition. Methods: A total of 112 patients with AECOPD and malnutrition who met the inclusion criteria were selected from October 2023 to February 2024. The patients were randomly divided into observation group and control group by random number table method. The control group was treated with standard Western medicine, and the observation group was treated with standard Western medicine combined with Shenqu Jianpi granule. The total cycle was 2 weeks. The changes of lung function, blood gas analysis index, CAT score, ALB and BMI of the two groups were observed and compared before and after treatment, the TCM syndrome score was evaluated, and the clinical efficacy of the two groups was compared. Results: The total effective rate of the observation group was significantly better than that of the control group (P 2), arterial partial pressure of carbon dioxide (PaCO2), CAT

关 键 词：慢性阻塞性肺疾病 营养不良 参曲健脾颗粒 

分 类 号：R56[医药卫生—呼吸系统]