儿童慢性活动性EB病毒感染相关性噬血细胞综合征1例并文献复习  

One Case of Chronic Active EB Virus Infection Associated Hemophagocytic Syndrome in Children and Literature Review

作　　者：张淑红[1] 刘霞[2] 

机构地区：[1]山东大学附属威海市立医院儿科,山东 威海 [2]山东大学附属威海市立医院影像科,山东 威海

出　　处：《临床医学进展》2024年第10期539-542,共4页Advances in Clinical Medicine

摘　　要：目的:总结1例慢性活动性EB病毒感染相关性噬血细胞综合征患儿的临床特点及诊疗经过,提高对该疾病的认识。方法:回顾性分析2022年10月山东大学附属威海市立医院儿科收治的1例慢性活动性EB病毒感染相关性噬血细胞综合征患儿的临床特点及诊疗经过,并进行相关文献复习。结果:患儿以发热、反复肝损害、全血细胞减少、凝血功能紊乱为突出表现,病情发展迅速,短时间内死亡,结合相关检查,诊断为慢性活动性EB病毒感染相关性噬血细胞综合征。结论:对于慢性活动性EB病毒感染患儿,在明确诊断后应积极采取有效治疗措施,一旦引起相关噬血细胞综合征,死亡率极高。Objective: To summarize the clinical characteristics and diagnosis and treatment process of a child with chronic active EB virus infection associated hemophagocytic syndrome, and improve the understanding of this disease. Methods: Retrospective analysis of the clinical characteristics and diagnosis and treatment process of a child with chronic active EB virus infection associated hemophagocytic syndrome admitted to the pediatrics department of Weihai Municipal Hospital affiliated with Shandong University in October 2022, and relevant literature review. Results: The child presented with prominent symptoms such as fever, repeated liver damage, decreased whole blood cells, and coagulation dysfunction. The condition developed rapidly and died within a short period of time. Combined with relevant examinations, the diagnosis was chronic active EB virus infection associated hemophagocytic syndrome. Conclusions: For children with chronic active EB virus infection, effective treatment measures should be actively taken after a clear diagnosis. Once it causes related hemophagocytic syndrome, the mortality rate is extremely high.

关 键 词：慢性活动性EB病毒感染 儿童 噬血细胞综合征 

分 类 号：R72[医药卫生—儿科]