小儿原发性肾病综合征并发血栓栓塞的危险因素分析  

Analysis of Risk Factors for Complicated Thromboembolism in Pediatric Primary Nephrotic Syndrome

作　　者：戴蕾莲 许晓蕾 

机构地区：[1]山东大学附属威海市立医院儿内科,山东 威海

出　　处：《临床医学进展》2024年第12期108-111,共4页Advances in Clinical Medicine

摘　　要：目的:分析小儿原发性肾病综合征(PNS)并发血栓栓塞的危险因素。方法:回顾性分析本院于2022年2月~2023年2月期间收治的患儿,将50例发生栓塞患儿设为观察组,另选取同期入院治疗未发生栓塞的50例患者设为对照组,比较两组患儿之间各指标差异,并进行多因素logistic回归分析主要因素。结果:两组患儿在感染、利尿剂使用、白细胞计数、IgG、补体C3、总蛋白、白蛋白、尿素氮、血浆纤维蛋白原、D-二聚体、抗凝血酶、24 h尿蛋白定量各指标差异显著,具有统计学意义(p Objective: To analyze the risk factors of thromboembolism in pediatric primary nephrotic syndrome (PNS). Methods: In a retrospective analysis of children admitted from February 2022 to February 2023, 50 children with embolization were set as the observation group, and 50 patients without embolization in the same period were selected as the control group to compare the differences between the two groups, and multifactor logistic regression was conducted to analyze the main factors. Results: Infection, diuretic use, leukocyte count, IgG, complement C3, total protein, albumin, urea UN, plasma fibrinogen, D-dimer, antithrombin, and 24 h urinary protein between the two groups are significantly different, which has statistical significance (p < 0.05);logistic regression equation analysis, D-dimer and 24 h proteinuria were the main risk factors. Conclusion: Clinically, for children with PNS, attention should be paid to the D-dimer and 24 h proteinuria quantification to prevent thromboembolism.

关 键 词：肾病综合征 血栓栓塞 危险因素 小儿 

分 类 号：R72[医药卫生—儿科]