甘油三酯葡萄糖指数联合肥胖相关指标预测2型糖尿病发生风险的研究进展  

Research Progress of Triglyceride Glucose Index Combined with Obesity-Related Indicators in Predicting the Risk of Type 2 Diabetes Mellitus

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作  者:陈凌煜 时晔[2] 

机构地区:[1]西安医学院研究生部,陕西 西安 [2]陕西省人民医院全科医学科,陕西 西安

出  处:《临床医学进展》2024年第12期1365-1370,共6页Advances in Clinical Medicine

摘  要:胰岛素抵抗(IR)是肥胖和T2DM的共同病理生理基础。肥胖相关指标作为2型糖尿病(T2DM)的危险因素,也是其进展的重要原因。体重指数(BMI)作为肥胖的依据指标,成为大多数T2DM风险模型的变量之一,然而,对于中心性肥胖或老年人群,BMI及其他肥胖相关其他指标的预测能力有限。甘油三酯葡萄糖 (TyG)指数操作简单、经济易得,可作为IR评价指标。近年研究发现TyG指数与肥胖相关指标对T2DM发病风险预测作用更好,本文就TyG指数联合肥胖相关指标对T2DM的预测价值作一综述。Insulin resistance (IR) is the common pathophysiological basis for obesity and T2DM. Obesity-related indicators, as risk factors of type 2 diabetes mellitus (T2DM) and important reasons for its progress. Body Mass Index (BMI), as a basis indicator for obesity, has become one of the variables in most T2DM risk models. However, the predictive power of BMI and other obesity related indicators is limited for central obesity or elderly populations. The triglyceride glucose (TyG) index is simple to operate and economical to obtain, and can be used as an IR evaluation index. In recent years, it has been found that TyG index and obesity-related indicators play a better role in predicting the risk of T2DM. This article reviews the predictive value of TyG index combined with obesity-related indicators on T2DM.

关 键 词:甘油三酯葡萄糖指数 肥胖相关指标 胰岛素抵抗 2型糖尿病 

分 类 号:R58[医药卫生—内分泌]

 

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