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出 处:《临床医学进展》2025年第3期999-1007,共9页Advances in Clinical Medicine
摘 要:妊娠是一个复杂的生理过程,在整个过程中,母体的多个系统——包括生殖、泌尿、呼吸、血液、循环、消化、皮肤、代谢以及骨骼关节等——将随着孕期的推进而有所改变。与此同时,一些合并症也会随之而来,如妊娠期糖尿病、妊娠期高血压疾病、妊娠期甲状腺异常、妊娠期贫血等。在诸多并发症中,妊娠期高血压尤为普遍,而子痫前期(preeclampsia, PE)是其最严重的表现形式之一。近年来,有研究不断揭示胎盘早剥(placental abruption, PA)的发生与子痫前期有着紧密的关联。胎盘早剥作为一种严重的妊娠期并发症,对母体和胎儿的健康构成了极大的威胁,如造成胎儿宫内窘迫、早产、死产、产后大出血、弥散性血管内凝血(DIC)、急性肾衰竭等一系列危及母儿生命的不良妊娠结局。因此,及时识别和治疗胎盘早剥显得尤为关键。这不仅对于减少不良母婴结局的发生有着重大影响,而且也为提升母婴健康水平奠定了坚实的基础。Pregnancy is a complex physiological process. During this process, multiple systems of the maternal body, including the reproductive, urinary, respiratory, blood, circulatory, digestive, skin, metabolic, and skeletal-joint systems, will experience significant changes as the pregnancy progresses. At the same time, pregnant women may encounter a series of complications, such as gestational diabetes, hypertensive disorders of pregnancy, thyroid abnormalities during pregnancy, and gestational anemia. Among these complications, hypertensive disorders of pregnancy are particularly common, and preeclampsia (PE) is one of its most severe manifestations. In recent years, a growing number of studies have continuously revealed a close association between placental abruption (PA) and preeclampsia. As a serious pregnancy-related complication, placental abruption poses a great threat to the health of both the mother and the fetus, leading to a series of adverse pregnancy
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