2型DKD患者血清焦亡相关蛋白与肾损伤的分析  

Analysis of Serum Pyrodeath Re-lated Proteins and Renal Injury in Patients with Type 2 DKD

作　　者：马茹洁 巴应贵[1] 

机构地区：[1]青海大学附属医院,青海 西宁

出　　处：《亚洲急诊医学病例研究》2023年第2期53-58,共6页Asian Case Reports in Emergency Medicine

摘　　要：糖尿病肾病(DKD)是糖尿病最常见的并发症之一,也是导致终末期肾病的主要原因。全球30%~40%糖尿病患者因病情迁延而进展至DKD,伴有终末期肾病的患者五年生存率 < 20%。因此,延缓DKD进展对于改善患者生存质量具重大意义。目前研究发现,2型DKD发病进展中的无菌性炎症机制与病情进展密切相关。Diabetic nephropathy (DKD) is one of the most common complications of diabetes and the main cause of end-stage renal disease. Globally, 30%~40% of diabetic patients progress to DKD due to disease delay, and the five-year survival rate of patients with end-stage re-nal disease is less than 20%. Therefore, delaying DKD progression is of great significance for im-proving patients’ quality of life. Current studies have found that the aseptic inflammatory mecha-nism in the progression of type 2 DKD is closely related to the progression of the disease.

关 键 词：2型糖尿病肾病 细胞焦亡 NLRP3炎症小体 肾损伤 

分 类 号：R58[医药卫生—内分泌]