嗜酸性肉芽肿性血管炎合并膜性肾病病例报告1例及文献复习  

A Case Report of Eosinophilic Granulomatosis with Polyangiitis Combined with Membranous Nephropathy and Literature Review

作　　者：蔡雨芹 于白莉[2] 马淑婷 杨梅婕 

机构地区：[1]成都中医药大学临床医学院,四川 成都 [2]成都中医药大学附属医院,四川 成都

出　　处：《亚洲急诊医学病例研究》2025年第1期90-93,共4页Asian Case Reports in Emergency Medicine

摘　　要：嗜酸性肉芽肿性血管炎(EGPA)是一种罕见的多系统性小血管炎,膜性肾病(MN)是导致肾病综合征的常见病因,其特点是肾小球基底膜出现免疫复合物沉积。尽管EGPA合并MN的病例较为罕见,但其潜在的病理机制可能涉及免疫系统的异常激活和自身免疫反应。本文报道1例嗜酸性肉芽肿性血管炎合并膜性肾病典型病例,总结其诊治要点,并复习相关文献。Eosinophilic Granulomatosis with Polyangiitis (EGPA) is a rare multi-systemic small-vessel vasculitis. Membranous Nephropathy (MN) is a common cause of nephrotic syndrome, characterized by immune complex deposition in the glomerular basement membrane. Although cases of EGPA combined with MN are rare, the underlying pathological mechanism may involve abnormal activation of the immune system and autoimmune reactions. This article reports a typical case of EGPA combined with MN, summarizes the key points of diagnosis and treatment and reviews relevant literature.

关 键 词：嗜酸性肉芽肿 血管炎 膜性肾病 

分 类 号：R69[医药卫生—泌尿科学]