蝉花和蝙蝠蛾拟青霉复合浸泡虫草酒免疫活性研究  

Study on the Immune Activity of Combined Cordyceps Wine of Cordyceps cicadae and Paecilomyces hepiali

作　　者：张莹莹 周怡倩 徐志香 于士军[1] 彭国杰 胡建峰 孙长胜 

机构地区：[1]安徽农业大学,安徽 合肥 [2]滁州学院,安徽 滁州 [3]浙江泛亚生命科学研究院,浙江 平湖

出　　处：《微生物前沿》2020年第2期60-65,共6页Advances in Microbiology

摘　　要：本文通过0.45 g/kg∙BW/d (低剂量)和0.9 g/kg∙BW/d (高剂量)两个剂量组的复合虫草酒经口给予小鼠饲喂1个月实验,进行小鼠免疫器官系数、体液免疫功能和单核巨噬细胞活性的测定,研究复合虫草酒的免疫调节作用。结果表明,高剂量组复合虫草酒能够显著提高小鼠抗体积数,较空白对照组提高了62.94%;高、低剂量组均能明显提高小鼠的鸡红细胞吞噬指数,较对照组分别提高了44%和40%,吞噬百分率分别较对照组分别提高了21.57%和19.61%。高剂量组复合虫草酒具有提高小鼠抗体积数和增强小鼠单核巨噬细胞吞噬活性的作用。In the present study, combined Cordyceps wine of the two dose groups of 0.45 g/kg∙BW/d (low dose) and 0.9 g/kg∙BW/d (high dose) were administered orally to mice for 1 month. Coefficients of immune organs, humoral immune function and mononuclear macrophage activities were determined to study the immune function of combined Cordyceps wine. The results indicated that the combined Cordyceps wine in the high-dose group could significantly increase the numbers of antibody of mice, which was 62.94% higher than that in the blank control group. The high-dose and low-dose groups could significantly increase phagocytic index of the chicken’s erythrocyte, accounting for 44% and 40% higher than that of the control group. The percentages of phagocytosis increased by 21.57% and 19.61%, respectively, compared with the control group. The high-dose group of combined Cordyceps wine had an effect on increasing numbers of antibodies and enhancing the phagocytic activity of mononuclear macrophages of mice.

关 键 词：复合虫草酒 蝉花 蝙蝠蛾拟青霉 免疫调节 

分 类 号：R28[医药卫生—中药学]