氧化亚铜/银异质结构的生物硫化氢检测性能研究  

Study on the Performance of Cu2O/Ag Heterostructure for Bio-H2S Detection

作　　者：刘晓娜 厉壬承 张晓宁 耿炜宏 王浩霖 孟沂 

机构地区：[1]临沂大学物理与电子工程学院,山东 临沂

出　　处：《应用物理》2024年第4期214-219,共6页Applied Physics

摘　　要：H2S被证实是人体内一种非常重要的内源性气体信号分子,其在人体内的含量会随着某些疾病的发生而变化,对于冠心病患者血浆中H2S的含量下降49.56%,提示内源性H2S参与冠心病发病过程。因此,水溶性H2S可作为冠心病等心血管疾病诊断的生物标志物,实现生物体内H2S浓度的快速检测可以达到冠心病及时监测的目的,对人类健康具有重要的意义。本项目旨在通过二维电化学沉积方法制备具有清晰异质界面的Cu2O/Ag纳微异质结构,基于氧化亚铜与银纳米线之间的异质结构势垒和样品与电极之间的肖特基势垒的双重调节作用,实现了硫化氢的高灵敏检测,且响应时间短,可靠性高。该研究可以为基于Cu2O的异质结构的传感材料的制备提供新的思路。Hydrogen sulfide (H2S) has been proven to be a very important endogenous gas signaling molecule in the human body, and its content in the body will change with the occurrence of certain diseases. For patients with coronary heart disease, the content of H2S in the plasma decreases by 49.56%, suggesting that endogenous H2S is involved in the pathogenesis of coronary heart disease. Therefore, water-soluble H2S can be used as a biomarker for the diagnosis of cardiovascular diseases such as coronary heart disease. Rapid detection of H2S concentration in biological bodies can achieve the purpose of timely monitoring coronary heart disease, which is of great significance to human health. This project aims to build Cu2O/Ag nano-micro heterogeneous structures with clear heterogeneous interfaces by two-dimensional electrochemical deposition method, based on the double regulation of the heterogeneous barrier between Cuprous oxide and silver nanowires and the Schottky barrier between sample and electrode, high sensitivity detection of hydrogen sulfide is achieved with short response time and high reliability. This study can provide new ideas for the preparation of sensing materials based on Cu2O heterostructures.

关 键 词：H₂S Cu₂O/Ag异质结构 电沉积 

分 类 号：R54[医药卫生—心血管疾病]