基于药用价值的金果榄凝胶剂制备及质量评价  

Preparation and Quality Evaluation of Radia tinosporae Gel Based on Medicinal Value

作　　者：张嗣伟 郭振超 常莹莹 刘鑫 杨新明 张新勇 

机构地区：[1]安徽科技学院生命与健康科学学院,安徽 滁州 [2]安徽科技学院马克思主义学院,安徽 滁州

出　　处：《生物过程》2023年第4期161-169,共9页Bioprocess

摘　　要：本研究以金果榄和冰片为原料,制备一种金果榄凝胶,对其提取工艺优化并做出质量评价。方法:采用正交实验法,研究最佳的金果榄浸提工艺,以获得最佳色泽的漉液,后加入冰片、聚乙烯醇缩甲乙醛等辅料,再通过一定的浓缩加热,即得。结果:在以25℃为提取温度、1:4为固液比、浸提时间48 h时,获得的金果榄凝胶在颜色、粘度、性状各方面都是最佳的。冰片40%、聚乙烯醇缩甲乙醛40%时,所得到的金果榄凝胶的性状最佳。结论:在温度为25℃,固液比为1:4,浸提时间为48 h时有最优实验方案。针对金果榄的提取工艺,采取正交试验的方法来进行研究,可以最大程度对试验结果进行系统检测、鉴定和分析,为金果榄新剂型的开发和利用提供科学依据。In this paper, a kind of Radix tinosporae gel was prepared with Radix tinosporae and borneol as raw materials, and the quality evaluation of its better extraction process and method was made. Method: Use orthogonal experiment method to study the best extraction process of Radix tinosporae ram to obtain the best color and luster, then add borneol, polyvinyl acetaldehyde and other auxiliary materials, and then pass certain concentration and heating, namely Radix tinosporae gel. Results: When the extraction temperature was 25˚C, the solid-liquid ratio was 1:4, and the extraction time was 48 h, the Radix tinosporae gel obtained was the best in terms of color, viscosity, and properties. When borneol was 40% and polyvinyl acetal was 40%, the properties of the Radix tinosporae gel obtained were the best. Conclusion: According to the above factors, there was an optimal experimental design when the temperature was 25˚C, the solid-liquid ratio was 1:4, and the extraction time was 48 h. For the extraction process of Radix tinosporae, the orthogonal test method was adopted to conduct research, which could provide a scientific basis for the development and utilization of Radix tinosporae to the greatest extent, and conduct accurate systematic detection, identification and analysis of the test results.

关 键 词：金果榄 凝胶剂 提取工艺 正交试验 

分 类 号：R28[医药卫生—中药学]