生物活性玻璃在疾病治疗中的应用进展  

Advances in the Application of Bioactive Glass in Disease Treatment

作　　者：求毓文 

机构地区：[1]南京医科大学口腔医学院,江苏 南京

出　　处：《生物医学》2025年第2期318-327,共10页Hans Journal of Biomedicine

摘　　要：生物活性玻璃是一种具有高度生物相容性和生物活性的非晶态材料,其主要成分通常包括二氧化硅、氧化钙、氧化钠和氧化磷等,能与生物体骨骼形成牢固的化学键或生物降解形成新骨骼,因此在疾病治疗方面已经取得了显著进展,特别是骨和软组织再生、口腔科修复以及特定慢性疾病的治疗等方面。近期的研究还聚焦于生物活性玻璃的多功能化,例如通过掺入金属离子或稀土元素赋予其抗炎抗菌、光热治疗、荧光监测等功能,为生物活性玻璃在疾病治疗中的应用提供了新的视角与策略。Bioactive glass is an amorphous material with high biocompatibility and bioactivity. Its main components typically include SiO2, CaO, Na2O and P2O5, which can form strong chemical bonds with the body’s bones or biodegrade to form new bone tissue. Therefore, significant progress has been made in the treatment of diseases, especially in bone and soft tissue regeneration, dental restoration, and the treatment of specific chronic diseases. Recent research has also focused on the functionalization of bioactive glass, such as incorporating metal ions or rare earth elements to endow it with anti-inflammatory, antibacterial, photothermal therapy, and fluorescence monitoring capabilities. These advancements provide new perspectives and strategies for the application of bioactive glass in disease treatment.

关 键 词：生物活性玻璃 疾病治疗 生物成像 生物传感器 药物载体 

分 类 号：R318.08[医药卫生—生物医学工程]