金雀花碱药理作用研究进展  

Advances in Pharmacological Action of Cytisine

作　　者：季宇彬[1] 张晓璐 刘洋[2] 杨斯伦 刘颖杰[1] 

机构地区：[1]哈尔滨商业大学生命科学与环境科学研究中心,黑龙江哈尔滨 [2]哈尔滨医科大学附属第二医院静配中心,黑龙江哈尔滨

出　　处：《药物化学》2018年第4期90-96,共7页Hans Journal of Medicinal Chemistry

摘　　要：以近年来国内外研究金雀花碱的报道为基础,对金雀花碱的药理作用及药代动力学研究进展进行综述。金雀花碱具有戒烟、增强心肌收缩力、兴奋呼吸、增强运动能力、改善认知功能、抗抑郁、镇痛、抗肿瘤等药理作用,是一种极具应用价值的药物,具有广阔的发展前景。Based on the reports of studies on cytisine in China and abroad in recent years, the research progress on the pharmacological effects and pharmacokinetics of cytisine are summarized. Cytisine has the pharmacological effects on smoking cessation, enhancing myocardial contractility, sti-mulating respiration, enhancing locomotor activity, improving cognitive function, anti-depression, analgesic, anti-tumor and so on. It is a drug with great application value and broad development prospects.

关 键 词：金雀花碱 药理作用 药代动力学 

分 类 号：R28[医药卫生—中药学]