睡眠呼吸障碍综合征及睡眠姿势与屈光参差的关系  

The Relationship between Sleep Posture and Anisometropia in Patients with Obstructive Sleep Apnea-Hypopnea Syndrome

作　　者：赵华轩[1,2] 高莹莹 于杨[1] 陈晓阳 樊冀闽[3] 

机构地区：[1]福建医科大学附属第二医院眼科,福建 泉州 [2]南通大学附属东台医院眼科,江苏 东台 [3]福建医科大学附属第二医院呼吸与危重症医学科,福建 泉州

出　　处：《眼科学》2021年第2期50-58,共9页Hans Journal of Ophthalmology

摘　　要：目的:研究探讨阻塞性睡眠呼吸暂停综合征(OSAHS)及不同睡眠姿势与屈光参差的关系。方法:横断面研究,收集在我院呼吸科行多导睡眠监测并确诊为OSAHS的患者61例作为OSA组,年龄匹配的健康人群67例作为对照组,对所有研究对象询问相关个人基本资料及病史,进行眼部检查:电脑验光、角膜地形图及眼轴测定。并根据习惯睡眠姿势将OSA组患者分为侧睡组(OSA-S组)及非侧睡组(OSA-NS组),对照组分为侧睡组(Control-S组)及非侧睡组(Control-NS组)。分析屈光参差、角膜地形图参数及眼轴长度在各组的差异。结果:OSA组屈光参差发生率为(29/61, 47.54%)高于对照组(11/67, 16.42%) (χ2 = 14.40, P 【0.05)。OSA-S组屈光参差发生率(22/32, 68.75%)分别高于OSA-NS组(7/29, 24.14%)、Control-S (4/24, 16.67%)组和Control-NS (7/43, 16.28%) (χ2 = 12.14, χ2 = 14.96, χ2 = 21.30, all P 【0.05)。轻、中、重度OSAHS屈光参差的发生率分别是20.00%、26.32%、68.75%,重度OSAHS患者屈光参差的发生率最高(重度vs轻度,χ2=3.95,P 【0.05;重度vs中度,χ2 = 6.25,P 【0.05)。角膜地形图检查:OSA组SRI (Surface Regularity Index )、SAI (Surface Asymmetry Index)、CYL (Cylinder)明显高于对照组(t = 82.65, t = 16.65, t = 5.88, all P 【0.05);OSA-S组侧睡侧眼SRI、SAI、CYL明显高于对侧眼(t = 10.66, t = 2.65, t = 3.47, all P 【0.05)。OSA-S组22名发生屈光参差者侧睡侧眼的眼轴长度大于对侧眼(Z = 1.70, P 【0.05)。结论:习惯单侧睡眠姿势的OSAHS患者,易发生屈光参差,侧睡侧眼近视程度较对侧重,并与OSAHS严重程度相关。Objective: To investigate the occurrence of anisometropia in patients with obstructive sleep apnea syndrome (OSAHS) in different sleeping posture. Methods: Cross-sectional study. Sixty-one patients diagnosed with OSAHS from the Second Affiliated Hospital of Fujian Medical University were sorted as OSA group. Sixty-seven healthy people were recruited as the Control group. All the cases were asked for personal information and medical history, and ophthalmological check-up involved computer optometry, corneal topography, and optical coherence interferometry. The patients in OSA group were divided into side sleeping group (OSA-S group) and non-side sleeping group (OSA-NS group) according to the habitual sleeping posture, and the control group was divided into side sleeping group (Control-S group) and non-side sleeping group (Control-NS group) on the same scenario. The differences in anisometropia, corneal topography parameters and eye axis length were analysed in each group. Results: The incidence of anisometropia in OSA group (29/61, 47.54%) was higher than that in control group (11/67, 16.42%) (χ2 = 14.40, P <0.05). The incidence of anisometropia in the OSA-S group (22/32, 68.75%) was higher than that in the OSA-NS group (7/29, 24.14%), Control-S (4/24, 16.67%) group, and Control-NS (7/43, 16.28%) (χ2 = 12.14, χ2 = 14.96, χ2 = 21.30, all P <0.05). The incidences of mild, moderate, and severe OSAHS anisometropia were 20.00%, 26.32%, and 68.75%, respectively. Severe OSAHS patients had the highest incidence of anisometropia (severe vs mild, χ2 = 3.95, P <0.05;Degree, χ2 = 6.25, P <0.05). Corneal topographic examination: OSA group SRI (Surface Regularity Index), SAI (Surface Asymmetry Index), CYL (Cylinder) were significantly higher than the control group (t = 82.65, t = 16.65, t = 5.88, all P <0.05);OSA -The SRI, SAI, and CYL of the sleeping side eye in the S group were significantly higher than that of the contralateral eye (t = 10.66, t = 2.65, t = 3.47, all P <0.05). In the OSA-S group, 22 p

关 键 词：屈光参差 阻塞性睡眠呼吸暂停综合征 睡眠姿势 角膜地形图 

分 类 号：R76[医药卫生—耳鼻咽喉科]