A型肉毒杆菌毒素治疗眼睑痉挛的临床分析  

Clinical Analysis of Botulinum Toxin Type A in the Treatment of Blepharospasm

作　　者：张雅婷 申洁 代应辉[1] 尹群 

机构地区：[1]蚌埠医学院第一附属医院眼科,安徽 蚌埠

出　　处：《眼科学》2024年第3期70-74,共5页Hans Journal of Ophthalmology

摘　　要：目的:探讨眼睑局部注射A型肉毒杆菌对于眼睑痉挛的效果。方法:收集2022年7月~2024年2月被我院确诊为特发性眼睑痉挛的患者资料,筛选出其中符合条件者共78例作为研究对象。所有受试者均给予眼睑局部多点A型肉毒杆菌毒素治疗。本次研究中,选取的观察指标包括药疗效果、维持时间与不良反应。结果:A型肉毒杆菌毒素眼睑局部注射后,观察到痉挛症状大多1~7天完全缓解,有效治疗率约为98.7%。药物疗效大多可以维持3~6个月左右,并且并发症少。结论:A型肉毒杆菌毒素对于特发性眼睑痉挛患者进行眼睑局部注射治疗效果显著而且副作用少见,值得在临床上推广使用。Objective: To investigate the effect of local injection of Botulinum Toxin Type A into eyelid for blepharospasm. Methods: Data of patients diagnosed with idiopathic blepharospasm in our hospital from July 2022 to February 2024 were collected, and a total of 78 eligible patients were selected as research objects. All subjects were treated with local eyelid multipoint Botulinum Toxin Type A. In this study, the observational indicators included therapeutic effect, maintenance time and adverse reactions. Results: The symptoms of spasmodic were completely relieved in 1~7 days with an effective rate of 98.7%. The effect usually lasts for 3~6 mouths with few complications. Conclusion: Botulinum Toxin Type A given by local injection on multiple sites is more effective than acupuncture and moxibustion in the treatment of idiopathic ocular and facial spasmodic.

关 键 词：A型肉毒杆菌毒素 特发性眼睑痉挛 

分 类 号：R24[医药卫生—中医临床基础]