经皮穴位电刺激对老年髋部骨折患者全髋关节置换术后免疫抑制状态的改善作用  

Improvement of Transcutaneous Electrical Acupoint Stimulation on Postoperative Immunosuppression in Elderly Patients with Hip Fracture Undergoing Total Hip Replacement

作　　者：丁淼 周雪飞 吴秋悦 王淑玉 曹云飞 

机构地区：[1]北仑区人民医院麻醉科,浙江 宁波 [2]北仑区人民医院教学部,浙江 宁波

出　　处：《外科(汉斯)》2025年第1期1-7,共7页Hans Journal of Surgery

基　　金：浙江省医药卫生科技计划项目(编号:2020KY917)。宁波市自然科学基金(编号:202003N4036)。

摘　　要：目的:探讨经皮穴位电刺激(TEAS)对老年髋部骨折患者全髋关节置换术后免疫抑制状态的改善作用。方法:选择2021年1月~2024年3月期间在北仑区人民医院初次行单侧全髋关节置换术的老年患者100例,随机分为经皮穴位电刺激组(TEAS组)和经皮穴位假电刺激组(SHAM组),每组50例。TEAS组患者于术前、术中及术后给予TEAS干预,SHAM组患者相应给予假TEAS干预。分别于术前1d及术后1 d、4 d、7 d检测两组患者的白介素-6 (IL-6)、C反应蛋白(CRP)水平,并比较两组之间的术后继发感染情况及术后住院天数。结果:组内与术前比较,两组患者术后1d和4d的血清IL-6及CRP水平均明显上升(P 0.05);组间比较,术后1d和4d的TEAS组血清IL-6水平均明显低于SHAM组(P 0.05)。结论:围术期TEAS能够明显改善老年髋部骨折患者全髋关节置换术后的免疫抑制状态,并降低术后感染的发生率。Objective: To observe the improvement of transcutaneous electrical acupoint stimulation (TEAS) on the postoperative immunosuppression in elderly patients with hip fracture undergoing total hip replacement. Methods: A total of 100 elderly patients with hip fracture scheduled for unilateral total hip replacement for the first time in Beilun District People’s Hospital from January 2021 to March 2024, were randomly divided into TEAS group and SHAM group, with 50 cases in each group. Patients in the TEAS group were given TEAS intervention before, during and after surgery, while patients in the SHAM group were treated with sham TEAS. The levels of interleukin-6 (IL-6) and C-reactive protein (CRP) were detected at 1 d before surgery, and 1 d, 4 d, 7 d after surgery respectively, and the incidence of postoperative infection and postoperative hospitalization days were compared between the two groups. Results: As compared with those before surgery, the serum levels of IL-6 and CRP in both groups were significantly increased at 1d and 4 d after surgery (P 0.05). Conclusion: Periop

关 键 词：经皮穴位电刺激 髋部骨折 全髋关节置换术 老年 免疫抑制 感染 

分 类 号：R24[医药卫生—中医临床基础]