基于肠道黏膜免疫功能探讨类风湿关节炎的中西医研究进展  

Research Progress of Chinese and Western Medicine on Rheumatoid Arthritis Based on Intestinal Mucosal Immune Function

作　　者：杨烁 佟颖[2] 

机构地区：[1]黑龙江中医药大学研究生院,黑龙江 哈尔滨 [2]黑龙江中医药大学附属第一医院肿瘤二科,黑龙江 哈尔滨

出　　处：《临床个性化医学》2024年第4期2291-2295,共5页Journal of Clinical Personalized Medicine

基　　金：黑龙江省自然科学基金联合引导项目(LH2019H115);黑龙江中医药大学“双一流”中西医结合学科发展助力基金(15041180133)。

摘　　要：类风湿关节炎是一种多发性关节炎性表现为主的全身性免疫性疾病,该疾病的病程多变,预后不佳,在治疗费用、致残率及社会劳动力等方面具有重大影响。目前对于该疾病的发病机制仍没有确切结论,但多方研究表明,肠道菌群失衡的状态下可能会诱发类风湿关节炎的发生和发展。这一发现为中西医结合的治疗策略提供了新的思路。Rheumatoid arthritis is a systemic autoimmune disease characterized by multiple arthritis. The course of the disease is variable and the prognosis is poor. It has a significant impact on treatment costs, disability rates, and social labor. At present, there is still no definite conclusion on the pathogenesis of the disease, but many studies have shown that the imbalance of intestinal flora may induce the occurrence and development of rheumatoid arthritis. This finding provides a new way for the treatment strategy of integrated traditional Chinese and Western medicine.

关 键 词：类风湿关节炎 肠道菌群 免疫 研究进展 

分 类 号：R59[医药卫生—内科学]