中医药治疗踝关节创伤性关节炎的机制与临床疗效研究进展  

Research Progress on the Mechanism and Clinical Efficacy of Traditional Chinese Medicine in the Treatment of Traumatic Arthritis of the Ankle Joint

作　　者：赵树超 陈世洲 毛国庆 

机构地区：[1]南京中医药大学第一临床医学院,江苏 南京 [2]南京中医药大学附属医院骨伤科,江苏 南京

出　　处：《临床个性化医学》2024年第4期2300-2305,共6页Journal of Clinical Personalized Medicine

摘　　要：踝关节创伤性关节炎(post-traumatic ankle arthritis, PTAA)是一种由外伤(如踝关节骨折或软组织损伤)引起的慢性退行性疾病,其临床特征包括持续性疼痛、活动受限以及功能障碍,严重影响患者的生活质量。该疾病的发病机制复杂,包括关节软骨的破坏、软骨下骨质的暴露及增生、持续性的炎症反应等。中医药治疗PTAA通过活血祛瘀、补益肝肾等手段,展示了在缓解疼痛、改善功能及抑制炎症等方面的多种疗效。本文旨在总结中医药在踝关节创伤性关节炎治疗中的作用机制及其临床疗效,为临床实践和未来研究提供参考。Post-traumatic ankle arthritis (PTAA) is a chronic degenerative disease caused by trauma (e.g., ankle fracture or soft-tissue injury), and its clinical features include persistent pain, activity limitation, and dysfunction, which seriously affects patients’ quality of life. The pathogenesis of this disease is complex, including destruction of articular cartilage, exposure and proliferation of subchondral bone, and persistent inflammatory response. Traditional Chinese medicine (TCM) treatment of PTAA demonstrates multiple efficacies in relieving pain, improving function, and inhibiting inflammation by activating blood circulation and eliminating blood stasis, and tonifying the liver and kidneys. The purpose of this article is to summarize the mechanism of action of TCM in the treatment of traumatic arthritis of the ankle and its clinical efficacy to provide reference for clinical practice and future research.

关 键 词：中医药疗法 踝关节创伤性关节炎 研究进展 

分 类 号：R68[医药卫生—骨科学]