基于数据挖掘探讨慢性支气管炎合并肺气肿的中医用药规律  

Data Mining-Based Analysis of Mechanism of Chinese Medication Rule in Treating Chronic Bronchitis Complicated with Emphysema

作　　者：陈小云 王雅莉 梁婷 杨瑞 陈录 李亚花 薛国琴 

机构地区：[1]云南中医药大学第一临床医学院,云南 昆明 [2]云南中医药大学第一附属医院/云南省中医医院肺病科,云南 昆明

出　　处：《临床个性化医学》2024年第4期2420-2428,共9页Journal of Clinical Personalized Medicine

摘　　要：目的:以数据挖掘为基础,分析总结中医辨证论治慢性支气管炎合并肺气肿的用药规律。方法:以中国知网CNKI、维普中文期刊服务平台以及万方医学网数据库平台为基础,检索2024年2月1日前已发表的,有关慢性支气管炎合并肺气肿的中医临床治疗文献,筛选出处方明确,且经过随机对照实验证明有效的期刊文献;使用SPSS Statistics、SPSS Modeler、古今医案云平台,分别对纳入的处方进行药物频次分析、性味归经分析、关联分析、聚类分析等。结果:数据库总计录入文献245篇,筛查出符合条件的处方46首,涉及中药123味;其中,中药药性以寒性药物为主;药味以甘、苦、辛味为主;药物多归入肺、脾、肾、心、胃经;高频中药有杏仁、半夏、甘草、麻黄、茯苓等。结论:中医临床治疗慢性支气管炎合并肺气肿多以宣肺平喘,理气化痰为原则;处方以三拗汤为基本方进行加减,根据证型进一步配伍清热、滋阴、温阳、利水渗湿等药物。Objective: Based on data mining, to analyze and summarize the rule of medicine in TCM dialectical treatment of chronic bronchitis complicated with emphysema. Methods: Based on CNKI, VIP Chinese journal service platform and Wanfang Medical network database platform, literature on TCM clinical treatment of chronic bronchitis complicated with emphysema published before February 1, 2024 was searched, and periodical literature with clear prescription and proven effective by randomized controlled experiments was selected. SPSS Statistics, SPSS Modeler and the cloud platform of ancient and modern medical records were used to analyze the drug frequency, sex and taste classification, association analysis and cluster analysis of the included prescriptions. Results: A total of 245 literatures were recorded in the database, 46 eligible prescriptions were screened, involving 123 flavors of traditional Chinese medicine. Among them, the medicinal properties of traditional Chinese med

关 键 词：数据挖掘 肺气肿 慢性支气管炎 中医 中药 性味归经 

分 类 号：R28[医药卫生—中药学]