Pd催化苯乙烯脱氢氧化偶联研究  

Pd(II)-Catalyzed Dehydrogenative Oxidative Coupling of Terminal Alkene of Styrene

作　　者：龚颖 王光祖[1] 

机构地区：[1]合肥工业大学医学工程学院,安徽合肥

出　　处：《有机化学研究》2015年第2期91-96,共6页Journal of Organic Chemistry Research

摘　　要：我们对未活化的苯乙烯末端烯烃进行了脱氢Heck反应的研究,运用Pd(acac)2做催化剂,Cu(OAc)2作氧化剂,并添加少量AgF,乙酸乙酯作溶剂,在100℃下反应24 h,苯乙烯直接脱氢得到1,4-二苯基-1,3-丁二烯,具有共轭结构,能作为许多有价值化合物的中间体,具有潜在的应用价值,我们还对该反应提出了一个可能的机理。The work about dehydrogenative Heck reaction of unactivated terminal alkene of styrene was studied. Using Pd(acac)2 as catalyst, Cu(OAc)2 as oxidant, EtOAc as solvent, and adding some AgF, at 100?C for 24 h, styrene was directly dehydrogenized to generate 1,4-dipheny-1,3-butadiene with conjugated construction which can be intermediate of many value compounds, so this reaction has potential value. A plausible mechanism was proposed.

关 键 词：苯乙烯 共轭二烯烃 脱氢Heck反应 

分 类 号：O62[理学—有机化学]