[Bmim]BF4催化下三组分一锅法合成多取代吡喃并[2,3-c]吡唑类化合物  

Three Components One-Pot Synthesis of Multi-Pyrane[2,3-c]pyrazoles Catalyzed by [Bmim]BF4

作　　者：梁杰 热孜亚·伊卜拉伊木 阿依古丽·巴拉提 Jie Liang;Raziya EbRayim;Aygul BaRat(Key Laboratory of Oil & Gas Fine Chemicals, Ministry of Education & Xinjiang Uyghur Autonomous Region, College of Chemistry and Chemical Engineering, Xinjiang University, Urumqi Xinjiang)

机构地区：[1]新疆大学化学化工学院,石油天然气精细化工教育部&自治区重点实验室,新疆乌鲁木齐

出　　处：《有机化学研究》2018年第2期39-44,共6页Journal of Organic Chemistry Research

基　　金：新疆教育部研究生科研创新项目基金(NO.XJGRI2014019)。

摘　　要：本文报道了在离子液体[Bmim]BF4催化条件下,以吡唑酮,芳香醛和丙二腈为起始原料经三组分一锅法合成多取代吡喃并[2,3-c]吡唑类化合物。该方法具有操作简便、选择性好、原子利用率高和环境友好等优点,为此类化合物的研究提供了一种有效的合成方法。目标产物的结构均通过IR,1H-NMR和HR-MS进行表征。This paper reports that on the catalytic condition of ionic liquid [Bmim]BF4, with pyrazolone, aromatic aldehyde and malononitrile as the starting materials, multi-pyrane[2,3-c]pyrazoles are synthesized by three-component one-pot reaction. This method has the advantages of simple operation, good selectivity, high atomic utilization rate and environmental friendliness, and provides an effective synthesis method for the study of these compounds. The structure of the products was characterized by IR, 1H-NMR and HR-MS.

关 键 词：离子液体 [BMIM]BF4 多组分反应 一锅法合成 吡喃并[2 3-c]吡唑类化合物 

分 类 号：O62[理学—有机化学]