2,3-Wittig反应的研究进展  

The Progress of [2,3]-Wittig Rearrangement

作　　者：陈书升[1] 王欢欢 张理明 

机构地区：[1]浙江师范大学,化学与生命科学学院,浙江 金华

出　　处：《有机化学研究》2022年第4期138-144,共7页Journal of Organic Chemistry Research

摘　　要：[2,3]-Wittig重排不同于传统的[3,3]-Claisen重排,自发现起得到了合成化学家的广泛关注,并得到了充分的研究。由于其能实现化学键高效简洁的转化,且能得到具有高度衍生化的含烯丙基的产物,[2,3]-Wittig重排在全合成领域具有重要的地位。本文旨在从该反应的最初发现、重排前体的构建、不对成重排的实现等方面,全面系统的介绍有别于传统[3,3]-Claisen重排的[2,3]-Wittig重排反应。[2,3]-Wittig rearrangement is an attractive reaction, which is extremely different from the traditional [3,3]-claisen rearrangement, and has received extensive attention from chemists since its initial discovery. Due to its efficient and concise transformation of chemical bonds and the ability to obtain highly derivatized allyl-containing products, [2,3]-Wittig rearrangement plays an important role in total synthesis. This review attempts to provide comprehensive knowledge about [2,3]-Wittig rearrangement, including initial discovery, construction of substrates, asymmetrical rearrangements, and so on.

关 键 词：[2 3]-Wittig重排 重排前体 烯丙基化 

分 类 号：O626[理学—有机化学]