经由Claisen重排的芳烃脱芳构化反应研究  

Study of Aromatics Dearomatization by Claisen Rearrangement

作　　者：樊锁江 刘冰杰 李泽彬 

机构地区：[1]浙江师范大学,化学与材料科学学院,浙江 金华

出　　处：《有机化学研究》2024年第1期1-16,共16页Journal of Organic Chemistry Research

摘　　要：Claisen重排作为一类重要的重排反应,反应过程中所经历的脱芳构化步骤具有其独特性。在有机合成中,脱芳构化反应是一种具有实用性的化学反应,芳香基团本身具有化学性质和功能,但有时也会构成一定障碍,在这种情况下,脱芳构化反应可以去除这些芳香基团,从而提高其稳定性并用于制备不同类型的化合物与功能分子。近些年来,随着新反应模式和新催化体系的发展创新,不同体系下的脱芳构化反应被相继报道。本文通过文献查阅,并进一步分析、归纳,对Claisen重排反应下的不同模式的脱芳构化进行了深入的探讨与研究,详细阐述了该类反应的独特机制和反应的发展情况。As a kind of important rearrangement reaction, the dearomatization process of Claisen rearrangement is unique. In organic synthesis, dearomatization reaction is a practical chemical reaction, the aromatic group itself has chemical properties and functions, but sometimes it will constitute a certain obstacle, in this case, dearomatization reaction can remove these aromatic groups, thereby improving its stability and used to prepare different types of compounds and functional molecules. In recent years, with the development and innovation of new reaction modes and new catalytic systems, dearomatization reactions under different systems have been reported successively. In this paper, through literature review, further analysis and induction, the different modes of dearomatization under Claisen rearrangement reaction are deeply discussed and studied, and the unique mechanism and development of this kind of reaction are elaborated in detail.

关 键 词：CLAISEN重排 脱芳构化 异位重排 

分 类 号：O62[理学—有机化学]