基于CRISPR/Cas系统的即时诊断研究进展  

Progress in Point-of-Care Diagnosis Based on CRISPR/Cas System

作　　者：杨赛男[1] 戴斌[1] 李平 刘宾 王诗琪 何昱嫦 吕圆 

机构地区：[1]湖南环境生物职业技术学院,湖南 衡阳

出　　处：《传感器技术与应用》2023年第6期493-504,共12页Journal of Sensor Technology and Application

摘　　要：面对突发公共卫生事件,快速、准确和便携的现场检测至关重要。基于CRISPR/Cas技术的分子诊断是目前现场检测主要方法,可以与多种信号传感方法相结合,集成到智能设备中,开发多个检测新平台。本文介绍基于CRISPR/Cas系统的传感器发展和现场应用,对CRISPR和现场检测的发展前景进行总结和展望。Fast, accurate and portable onsite testing is critical in the face of public health emergencies. Molecular diagnosis based on CRISPR/Cas technology is currently the main method of detection, which can be combined with a variety of signal sensing methods, integrated into smart devices, and develop multiple new detection platforms. This paper introduces the sensor development and field application based on CRISPR/Cas system, and summarizes and prospects the development prospect of CRISPR and field detection.

关 键 词：CRISPR/Cas 分子诊断 现场检测 

分 类 号：Q78[生物学—分子生物学]