单体CRP抗体检测在ANCA相关血管炎中的研究  

Detection of Monoclonal CRP Antibody in ANCA-Associated Vasculitis

作　　者：武凯丽 

机构地区：[1]内蒙古医科大学,内蒙古呼和浩特

出　　处：《医学诊断》2019年第2期66-70,共5页Medical Diagnosis

摘　　要：近些年来关于单体CRP的研究越来越广泛,单体CRP主要是对血管内皮产生作用,关于它的相关机制也是层出不穷,有关于它的研究遍布于外科学,包括对骨的影响,在免疫系统中的系统性红斑狼疮的研究更为热门,虽然在ANCA血管炎中关于单体CRP有所研究,但是关于它的作用机制,以及它对ANCA血管炎到底起了什么样的作用,这是一个值得我们深思的问题。ANCA血管炎这种疾病本身就是一个发展急剧的恶性疾病,只要和它相关的各项指标都应该引起一定的重视;本文旨在探讨单体CRP的作用机制,以及对各种疾病的影响,进而进一步研究,它对ANCA相关血管炎的作用机制,试图找出ANCA相关血管炎的疾病治疗作用的靶点。In recent years,the research on monomer CRP has become more and more extensive.Monomer CRP mainly plays an important role in vascular endothelium,and its related mechanisms emerge in endlessly.The research on monomer CRP is widespread in surgery,including the impact on bone.The research on systemic lupus erythematosus in immune system is more popular.Although monomer CRP has been studied in ANCA vasculitis,it is still a hot topic.It is a question worth pon-dering about its mechanism of action and what role it plays in ANCA vasculitis.ANCA vasculitis itself is a rapidly developing malignant disease,as long as its related indicators should be paid attention to;this paper aims to explore the mechanism of CRP monomer and its impact on various diseases,and further study its mechanism of action on ANCA-related vasculitis,trying to find out the target of disease treatment of ANCA-related vasculitis.

关 键 词：单体CRP 单体CRP作用机制 ANCA相关性血管炎 

分 类 号：R5[医药卫生—内科学]