酮咯酸氨丁三醇的药理作用及临床应用进展  

Progress in Pharmacological Action and Clinical Application of Ketorolac Tromethamine

作　　者：刘闵 李炬颖 赵集 杨敏[1] 郑军[1] 

机构地区：[1]延安大学附属医院,陕西 延安

出　　处：《医学诊断》2020年第3期182-187,共5页Medical Diagnosis

摘　　要：酮咯酸氨丁三醇为非甾体类抗炎药,可抑制前列腺素的合成,主要用于需要阿片水平镇痛药物的急性较严重疼痛的短期治疗,通常用于手术后镇痛,可用来替代或辅助阿片类药物。目前国内外已经对酮咯酸氨丁三醇用于镇痛方面开展了许多研究,本文对酮咯酸氨丁三醇的药理机制、临床应用进行综述。Ketorolac Tromethamine is a non-steroidal anti-inflammatory drug that inhibits the synthesis of prostaglandins. It is mainly used for short-term treatment of acute and severe pain requiring opioid level analgesics. It is usually used for postoperative analgesia and can be used as a substitute or adjuvant for opioids. Many studies have been carried out on ketorolac for analgesia at home and abroad. This article reviews the pharmacological mechanism and clinical application of ketorolac for analgesia.

关 键 词：酮咯酸氨丁三醇 药理作用 临床应用 

分 类 号：R28[医药卫生—中药学]