肾病综合征合并肺部感染宏基因组测序技术的诊断价值  

Diagnostic Value of Metagenomics Next-Generation Sequencing in Nephrotic Syndrome Complicated with Pulmonary Infection

作　　者：陈婷 付甜[2] 刘金彦[3] 

机构地区：[1]济宁医学院临床医学院,山东 济宁 [2]济宁市第一人民医院呼吸科,山东 济宁 [3]济宁市第一人民医院肾内科,山东 济宁

出　　处：《医学诊断》2022年第3期243-249,共7页Medical Diagnosis

摘　　要：肾病综合征(nephrotic syndrome, NS)是一种由机体免疫功能异常引起肾脏超微结构改变的肾脏疾病综合征。致病菌复杂的肺部感染(pulmonary infection, PI)是NS的常见并发症。宏基因组测序技术(metagenomics next-generation sequencing, mNGS)作为一种新兴的诊断技术,以其高敏感性的优势备受关注。本文针对mNGS对于NS合并PI的诊疗价值进行分析与探讨,为临床决策助一臂之力。Nephrotic syndrome is a kind of kidney disease syndrome caused by abnormal immune function. It is found that complicated pulmonary infection with pathogenic bacteria is a common complication of Nephrotic syndrome. Metagenomics next-generation sequencing, as a new diagnostic technology, has attracted much attention because of its high sensitivity. In this paper, the diagnosis and treatment value of mNGS for Nephrotic syndrome complicated with PI is analyzed and discussed, which will help clinical decision.

关 键 词：肾病综合征 肺部感染 宏基因组测序 

分 类 号：R563.1[医药卫生—呼吸系统]