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作 者:贾戌生 贾孟辉 王娜琳[1] 马玉炜 冯佳婷 王佩佩 刘丽 左艳丽
机构地区:[1]宁夏医科大学中医(回医)学院,宁夏银川 [2]宁夏医科大学第二附属医院,宁夏银川 [3]宁夏回医药现代化省部共建教育部重点实验室,宁夏银川
出 处:《药物资讯》2019年第5期172-179,共8页Pharmacy Information
基 金:国家自然科学基金(81260568);国家自然科学基金(81560816);国家自然科学基金(81760906).
摘 要:目的:探讨《回回药方》残卷方剂中巴豆之用量及炮制规律。方法:1) 用量:将《回回药方》残卷“众风门”篇和“杂证门”篇中含巴豆的73首方剂,按原文对巴豆每次服用量进行折算、归纳和整理;2) 炮制:对含巴豆方剂方后注中标识有炮制的原文进行梳理和分析。结果:1) 用量:73首方剂中,19首用量不详,余54剂巴豆每次服用均量为0.54克,最大每次服用量为2.124克。其中,残卷“众风门”之“左瘫右痪口眼呙斜类”18首含巴豆方剂,巴豆每次服用均量为0.561克,“疏风顺气类”4首每次服用均量为0.461克,“风癞紫白癜类”8首每次服用均量为0.578克,“众风杂治类”3首每次服用均量为0.743克,“胸膈风类”1首每次用量为0.408克,“暗风类”1首每次用量为0.3克;“杂证门”19首巴豆每次服用均量为0.732克。2) 炮制:《回回药方》残卷“众风门”篇和“杂证门”篇中含巴豆的73首方剂,只有4首对巴豆的炮制有“去壳心、制烧过者、去皮油、用木瓜炒或达达茴香炒”的特殊说明。结论:《回回药方》残卷方剂使用巴豆的每次服用均量(0.54克)、最大量(2.124克)远超现代药典规定量,其炮制方法较为传统(去壳心、去皮油和制熟)。Objective:To investigate the dosage and processing law of Croton in residual Hui Hui Prescription.Method:1)Dosage:The 73 prescriptions containing Croton in the Zhongfeng Category”and“Incurable Diseases Category”of residual Hui Hui Prescription will be converted,summarized and sorted according to the original text;2)Processing:The original text marked in the post-note of the croton-contained formula will be combed and analyzed.Results:1)Dosage:Among the 73 prescrip-tions,Croton’s dosage of 19 prescriptions is unknown.The remained Croton’s dosage of 54 prescriptions is 0.54 g,and the maximum dose is 2.124 g.Among them,there are 18 prescriptions containing Croton of“Left-Related Paralysis,Mouth-and Eye-Related Disorder”type in the“Zhongfeng Category”,the average dose of croton is 0.561 g,and the average dose of each of the 4 prescriptions of“sparing the wind and guiding qi”type is the 0.461 g,the average dose of the 8 samples of“Purpura and Vitiligo”type is 0.578 g,and the average dose of 3 prescriptions of“Zhongfeng Miscellaneous”type is 0.743 g.The average dose of 1 prescription of“Chest Hurricane”type is 0.408 g,and of“Dark Wind”type is 0.3 g;of 19 prescriptions in“Hybrid Category”is 0.732 g.2)Processing:“Zhongfeng Category”and“Miscellaneous Category”of the residual“Hui Hui Prescription”contain 73 prescriptions of Croton,only 4 of which have special instructions of"shelled,roasted,peeled,fried with papaya or dada fennel"for the processing of Croton.Conclusion:The average and maximum dose of the prescription containing croton in the“Hui Hui Prescription”is 0.54 g and 2.124 g,respectively,which are far more than the specified dosage of modern Pharmacopoeia prescriptions,whose processing method is more traditional(shelling,oil removal,and system,cooked).
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