毛蕊花糖苷药理活性和作用机制研究进展  

Advancements in the Pharmacological Activity and Mechanisms of Action of Verbascoside

作　　者：李琪 李慧娟 张兴江 吴建新[1] 黄庆 

机构地区：[1]中国药科大学中药学院,江苏 南京

出　　处：《药物资讯》2024年第5期438-450,共13页Pharmacy Information

摘　　要：毛蕊花糖苷(Verbascoside, VB),作为苯乙醇苷类多酚化合物中的代表性成分,广泛存在于肉苁蓉等多种药用植物中,具备丰富的生物活性。现代药理研究表明,VB不仅在抗炎、抗氧化、神经保护、抗癌上效果显著,还能抗菌,调节免疫系统,保护肝脏、肾脏和肺,缓解疲劳,促进伤口愈合,对多种疾病具有潜在的治疗价值。本文综述了近年来关于VB的药理活性和作用机制的研究,旨在为VB的深入研究与应用提供参考。Verbascoside (VB), a representative phenylethanoid glycoside polyphenolic compound, is abundantly found in various medicinal plants such as Cistanches Herba. Extensive biological activities have been documented. Modern pharmacological studies reveal that VB not only significantly benefits anti-inflammatory, antioxidant, neuroprotective, and anticancer activities, but also possesses antimicrobial properties, and protects the livers, kidneys and lungs. It alleviates fatigue and promotes wound healing, offering potential therapeutic value for multiple diseases. This paper reviews recent research on the pharmacological activities and mechanisms of action of VB, aiming to provide references for further research and application of VB.

关 键 词：毛蕊花糖苷 药理作用 研究进展 

分 类 号：R28[医药卫生—中药学]