桑黄有效成分及抗肿瘤作用机制研究  

Study on the Active Ingredients and Anti-Tumor Mechanism of Phellinus igniarius

作　　者：李天平[1] 轩贵平[1] 刘德勇[1] 杨娜[1] 梁忠厚[1] 

机构地区：[1]湖南环境生物职业技术学院医药技术学院,湖南 衡阳

出　　处：《中医学》2024年第3期530-536,共7页Traditional Chinese Medicine

摘　　要：本文首先对中药桑黄进行了详细介绍,包括其生长环境、分布范围以及药理作用。其次重点探讨了桑黄的有效成分,如多糖、黄酮和三萜类化合物,并研究了它们各自的药理作用及相互协同作用。在此基础上,提出了桑黄的抗肿瘤作用机制,包括直接抑制肿瘤细胞生长、诱导肿瘤细胞凋亡以及免疫调节等方面。紧接着,从分子生物学角度分析了桑黄的抗肿瘤作用机制,揭示了其与肿瘤细胞信号转导通路的关系。最后,总结了桑黄抗肿瘤的研究前景及未来发展方向,为相关领域的研究工作提供参考资料。In this paper, the traditional Chinese medicine Phellinus igniarius is introduced in detail, including its growth environment, distribution range and pharmacological effects. Secondly, the active components of Phellinus igniarius, such as polysaccharides, flavonoids and triterpenoids, were discussed, and their respective pharmacological effects and synergistic effects were studied. On this basis, the anti-tumor mechanism of Phellinus igniarius was proposed, including direct inhibition of tumor cell growth, induction of tumor cell apoptosis, and immune regulation. Then, the anti-tumor mechanism of Phellinus igniarius was analyzed from the perspective of molecular biology, and its relationship with tumor cell signal transduction pathway was revealed. Finally, the research prospect and future development direction of Phellinus igniarius anti-tumor are summarized, which provides reference materials for research work in related fields.

关 键 词：桑黄 有效成分 抗肿瘤 作用机制 价值分析 

分 类 号：R28[医药卫生—中药学]