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出 处:《中医学》2025年第2期560-565,共6页Traditional Chinese Medicine
摘 要:早发性卵巢功能不全(premature ovarian insufficiency, POI)主要以围绝经期症状,月经失调(月经稀少、甚至闭经)为主,伴有高促性腺激素、低雌激素水平等为主要表现,对女性的危害主要是提前出现的低雌激素状态以及生殖机能的提前衰退。中医认为,肾藏精贮天癸,主生殖,为先天之本,天癸至则月事如期而至,若肾精亏损,冲任血海空虚,不能按时盈满而溢则可见月经后期、月经量少甚至闭经等问题,因此肾精亏虚,天癸竭是引起POI发病的根本病机。朱鸿秋教授认为该病的发生以肾虚为主导,但临床中常兼有肝郁、脾虚、痰湿、瘀血,在治疗上根据月经周期分期论治,随证加减,并结合中医特色治疗综合调理,注重情志疗法,身心同治,必要时中西医结合诊治,临床疗效显著。Premature ovarian insufficiency (POI) is mainly characterized by perimenopausal symptoms, menstrual disorders (scanty menstruation or even amenorrhea), accompanied by high gonadotropin and low estrogen levels, etc. It is harmful to women because of the early appearance of a low estrogen state and the early decline of reproductive functions. According to Chinese medicine, the kidney stores essence and sexual stimulant essence, and is the main reproductive agent, which is the foundation of the innate nature, and when sexual stimulant essence arrives, menstruation occurs on schedule. If the kidney essence is deficient and the blood and organs are empty, and if they cannot fill up and overflow on time, then it can be seen that menstruation is late, and the amount of menstruation is small, and even amenorrhea is even a problem, etc. Therefore, the deficiency of the kidney essence and the depletion of sexual stimulant essence is the fundamental pathogenesis that causes the onset of POI. Prof. Zhu Hongqiu believes that the disease occurs with kidney deficiency as the leading cause, but in clinical practice, it is often accompanied by liver depression, spleen deficiency, phleg
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