基于数据挖掘探讨赵珂主任治疗月经后期的用药规律  

Discussion on the Medication Rules of Director Zhao Ke’s Treatment of Late Menstruation Period Based on Data Mining

作　　者：刘立煌 赵珂[2] 甘永康[2] 

机构地区：[1]天津中医药大学,天津 [2]天津市中医药研究院附属医院,天津

出　　处：《中医学》2025年第2期635-642,共8页Traditional Chinese Medicine

基　　金：畿辅医派学术源流与传承研究:流派交叉、融合及成果应用的系统分析。

摘　　要：目的:挖掘赵珂主任医师治疗月经后期的用药组方规律,为临床治疗该疾病提供参考。方法:整理赵珂主任2022年5月~2023年6月期间治疗月经后期的用药处方,录入Excel、SPSS Modeler 18.0平台和IBM SPSS statistics 25,采用关联规则、复杂系统聚类、聚类分析等统计方法对整理好的处方药物进行用药规律分析。结果:共收集处方210首,涉及中药198味。中药使用频次前十位依次为白芍、菟丝子、香附、山茱萸、甘草、川芎、党参、熟地黄、当归、肉苁蓉。常用药对有白芍–紫石英、香附–延胡索、川芎–桃仁、白芍–杜仲、白芍–北沙参、白芍–淫羊藿、白芍–黄精、川芎–红花、菟丝子–鹿角霜、白芍–鹿角霜等。通过高频药物聚类分析得到可能的新方组合4首。结论:利用数据挖掘技术,可初步揭示赵珂主任临床诊疗月经后期疾病的规律:从肝、脾、肾论治,多用白芍、菟丝子、山茱萸等补虚药以滋经血之源,在此基础上加以辨证,配伍香附、川芎、延胡索等药物理气活血调经,从而治愈疾病。本研究亦可用于中药新药候选处方的筛选。Objective: To explore the medication rules of Director Zhao Ke’s treatment of late menstruation period, and provide reference for the clinical treatment of this disease. Methods: The prescriptions of Director Zhao Ke’s treatment of late menstruation from May 2022 to June 2023 were collected, and recorded into Excel, SPSS Modeler 18.0 platform and IBM SPSS statistics 25. The medication rules of the collected prescriptions were analyzed by association rules, complex system clustering, cluster analysis and other statistical methods. Results: A total of 210 prescriptions were collected, involving 198 flavors of traditional Chinese medicine. The top ten frequency of traditional Chinese medicine were Baishao (Paeoniae Radix Alba), Tusizi (Cuscutae Semen), Xiangfu (Cyperus Rotundus), Shanzhuyu (Corni Fructus), Gancao (Radix Rh

关 键 词：赵珂 月经后期 数据挖掘 用药规律 

分 类 号：R28[医药卫生—中药学]