蛋白结合毒素清除材料的研究进展  

Research Progress on Protein-Bound Toxin Removal Materials

作　　者：楼昱宽 张苏华 

机构地区：[1]上海理工大学健康科学与工程学院,上海

出　　处：《比较化学》2023年第4期33-40,共8页Journal of Comparative Chemistry

摘　　要：随着平均寿命的上升,慢性肾脏病患者的人数与比例都在逐年增加。蛋白结合毒素已被证明是诱发多种尿毒症并发症的关键因素,而且传统血液透析无法对蛋白结合毒素产生良好的清除效果。近年来,有关蛋白结合毒素清除材料的研究呈增多趋势,本文将基于应用于血液透析与血液灌流的吸附材料两种类型来进行综述。As the average life expectancy increases, the number and proportion of patients with chronic kidney disease are increasing year by year. Protein-bound toxins have been shown to be a key factor in inducing a variety of uremic complications, and traditional hemodialysis cannot produce a good removal effect on protein-bound toxins. In recent years, research on protein-bound toxin removal materials has been increasing. This article will review based on two types of adsorbent materials used in hemodialysis and hemoperfusion.

关 键 词：蛋白结合毒素 吸附材料 血液灌流 血液透析 

分 类 号：R69[医药卫生—泌尿科学]