微波辐射有机药物合成研究进展  

Organic Drug Synthesis Assisted with Microwave Irradiation

作　　者：韩谢 邵开元 胡文祥[1,2,3] 

机构地区：[1]武汉工程大学化工与制药学院,湖北武汉 [2]北京神剑天军医学科学院华北祥鹄微波化学联合实验室,北京 [3]中国人民解放军战略支援部队航天系统部,北京

出　　处：《微波化学》2017年第1期15-21,共7页Journal of Microwave Chemistry

摘　　要：本文综述了近年微波辐射技术应用于加速有机药物合成中的部分主要反应类型,包括酰化反应、环合反应、不对称烷基化、消除反应、重排反应、还原反应等。相比传统经典有机合成反应,微波辐射具有缩短反应时间,提高产率,减少副产物等优势。因此,近年来发展十分迅速。In this paper, the main types of organic drug synthesis assisted with microwave irradiation in re-cent years have been reviewed, including acylation, cyclization, asymmetric alkylation, elimination, rearrangement and reduction reaction. Compared with the traditional method, microwave assisted synthesis can greatly improve the yield and shorten the reaction time. Therefore, the development of microwave assisted synthesis in recent years become very rapid.

关 键 词：有机合成 药物合成 微波辐射 

分 类 号：O62[理学—有机化学]