Seroprevalence and Associated Risk Factors of Hepatitis B and C among Inmates of Port Harcourt Maximum Security Custodial Centre  

作　　者：Barynem Vito-Peter Gift Mibilanyeofori Hart Aisha Dio Victory Chidinma Nwogu Nancy Obutor Ideozu Ozioma Chiagoziem Okoro Okadini Collins Albert Abigail Chisa Mike-Ogburia Priscilla Adonike Ogbakiri Chiziyara Orluibna Obunwo Moore Ikechi Mike-Ogburia Barynem Vito-Peter;Gift Mibilanyeofori Hart;Aisha Dio;Victory Chidinma Nwogu;Nancy Obutor Ideozu;Ozioma Chiagoziem Okoro;Okadini Collins Albert;Abigail Chisa Mike-Ogburia;Priscilla Adonike Ogbakiri;Chiziyara Orluibna Obunwo;Moore Ikechi Mike-Ogburia(Department of Medical Laboratory Science, Rivers State University, Port Harcourt, Nigeria;Department of Medical Laboratory Science, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria;Port Harcourt Maximum Security Custodial Centre, Rivers State Command, Port Harcourt, Nigeria;Department of Basic and Applied Biological Sciences, Ahmadu Bello University, Zaria, Nigeria;Kariden Specialist Hospital, Port Harcourt, Nigeria;Department of Health Services, Rivers State University, Port Harcourt, Nigeria)

机构地区：[1]Department of Medical Laboratory Science, Rivers State University, Port Harcourt, Nigeria [2]Department of Medical Laboratory Science, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria [3]Port Harcourt Maximum Security Custodial Centre, Rivers State Command, Port Harcourt, Nigeria [4]Department of Basic and Applied Biological Sciences, Ahmadu Bello University, Zaria, Nigeria [5]Kariden Specialist Hospital, Port Harcourt, Nigeria [6]Department of Health Services, Rivers State University, Port Harcourt, Nigeria

出　　处：《Advances in Infectious Diseases》2023年第2期159-182,共24页传染病进展（英文）

摘　　要：Hepatitis B (HBV) and Hepatitis C (HCV) are significant global public health burdens associated with liver cirrhosis, liver cancer and are responsible for over a million deaths yearly. Prisons and other confined facilities offer opportunities for the acquisition and transmission of infectious diseases such as hepatitis B and C during and after imprisonment. This study aimed to investigate the seroprevalence of Hepatitis B and Hepatitis C as well as their associated risk factors among inmates in the Port Harcourt Maximum Security Custodial Centre. A cross-sectional study was conducted among inmates incarcerated in the Port Harcourt Maximum Security Custodial Centre from July to December 2022, and 200 consenting subjects completed a structured questionnaire in addition to screening for the presence of HBsAg and anti-HCV antibodies. Data generated from this study was represented as frequency and percentages, and inferential statistics were carried out using chi-square with the aid of GraphPad Prism Software Version 9. Statistical significance was defined as a p-value of less than 0.05 at a 95% confidence interval. The seroprevalence of HBV was 4% while 3.5% was recorded for HCV with no cases of co-infections reported. HBV seroprevalence was significantly associated with blood oath and a history of surgery (p p < 0.05). The findings from the current study highlight a relatively lower prevalence of HBV and HCV amongst inmates in Port Harcourt in comparison to studies in Nigeria. These infections can be further controlled by multifaceted approaches by the prison personnel, administration, and Government by employing combative measures such as regular screening, easy access to therapy, awareness, and vaccination programs for HBV are crucial to prevent the transmission of these diseases.Hepatitis B (HBV) and Hepatitis C (HCV) are significant global public health burdens associated with liver cirrhosis, liver cancer and are responsible for over a million deaths yearly. Prisons and other confined facilities offer opportunities for the acquisition and transmission of infectious diseases such as hepatitis B and C during and after imprisonment. This study aimed to investigate the seroprevalence of Hepatitis B and Hepatitis C as well as their associated risk factors among inmates in the Port Harcourt Maximum Security Custodial Centre. A cross-sectional study was conducted among inmates incarcerated in the Port Harcourt Maximum Security Custodial Centre from July to December 2022, and 200 consenting subjects completed a structured questionnaire in addition to screening for the presence of HBsAg and anti-HCV antibodies. Data generated from this study was represented as frequency and percentages, and inferential statistics were carried out using chi-square with the aid of GraphPad Prism Software Version 9. Statistical significance was defined as a p-value of less than 0.05 at a 95% confidence interval. The seroprevalence of HBV was 4% while 3.5% was recorded for HCV with no cases of co-infections reported. HBV seroprevalence was significantly associated with blood oath and a history of surgery (p p < 0.05). The findings from the current study highlight a relatively lower prevalence of HBV and HCV amongst inmates in Port Harcourt in comparison to studies in Nigeria. These infections can be further controlled by multifaceted approaches by the prison personnel, administration, and Government by employing combative measures such as regular screening, easy access to therapy, awareness, and vaccination programs for HBV are crucial to prevent the transmission of these diseases.

关 键 词：Hepatitis B Hepatitis C HBV HbsAg HCV PREVALENCE Risk Factors PRISON INMATES 

分 类 号：R51[医药卫生—内科学]