Hormonal Status Assessment of Infertile Congolese Men  

作　　者：Constantin Moukouma Henriette Poaty Rancia Colombe Diakouka Diambalou Ulrich Ngoma-Nzaou Guy Emergence Poaty Etienne Mokondjimobé Anani Wencesl Sévérin Odzebé Constantin Moukouma;Henriette Poaty;Rancia Colombe Diakouka Diambalou;Ulrich Ngoma-Nzaou;Guy Emergence Poaty;Etienne Mokondjimobé;Anani Wencesl Sévérin Odzebé(Institute of Research of Health Sciences, Brazzaville, Congo;Faculty of Health Sciences, Marien Ngouabi University, Brazzaville, Congo;National Laboratory of Public Health, Brazzaville, Congo;Health Priority Cabinet, Brazzaville, Congo;Teaching Hospital of Brazzaville, Brazzaville, Congo)

机构地区：[1]Institute of Research of Health Sciences, Brazzaville, Congo [2]Faculty of Health Sciences, Marien Ngouabi University, Brazzaville, Congo [3]National Laboratory of Public Health, Brazzaville, Congo [4]Health Priority Cabinet, Brazzaville, Congo [5]Teaching Hospital of Brazzaville, Brazzaville, Congo

出　　处：《Advances in Reproductive Sciences》2024年第2期155-164,共10页生殖科学（英文）

摘　　要：Background: The pathologies causing male infertility are various (congenital or acquired) and concern several hormone-producing organs: the hypothalamus, pituitary gland, testes and adrenals. The hormonal dosage includes systematically testosterone, FSH and LH. These analyses often highlight hypogonadism hypogonadotropic or hypergonadotropic. They can sometimes be normal. The present study aimed to establish the hormonal profile of infertile men residing in Brazzaville. Patients and Methods: It was a cross-sectional descriptive study during five years (from 2018 to 2023). It concerned 344 infertilemen with an abnormal spermogram and spermocytogram. The method was performed from the blood dosage of testosterone, FSH, and LH using the Elisa technique. Results: The hormonal assessment was not normal in 48.83% (168/344) of cases. Increased values of testosterone were noted in 6.10% of cases and decreased in 12.20%. Abnormal high values of FSH were observed in 14.24% of cases and decreased values in 8.13%. LH was elevated, i.e. 2.03% of cases and decreased in 6.10% of subjects. Conclusions: A hormonal disturbance was observed in almost half of the infertile men. It concerned the hypothalamus-pituitary and the testes axis and indicated mainly a state of hypogonadism with high FSH and low LH.Background: The pathologies causing male infertility are various (congenital or acquired) and concern several hormone-producing organs: the hypothalamus, pituitary gland, testes and adrenals. The hormonal dosage includes systematically testosterone, FSH and LH. These analyses often highlight hypogonadism hypogonadotropic or hypergonadotropic. They can sometimes be normal. The present study aimed to establish the hormonal profile of infertile men residing in Brazzaville. Patients and Methods: It was a cross-sectional descriptive study during five years (from 2018 to 2023). It concerned 344 infertilemen with an abnormal spermogram and spermocytogram. The method was performed from the blood dosage of testosterone, FSH, and LH using the Elisa technique. Results: The hormonal assessment was not normal in 48.83% (168/344) of cases. Increased values of testosterone were noted in 6.10% of cases and decreased in 12.20%. Abnormal high values of FSH were observed in 14.24% of cases and decreased values in 8.13%. LH was elevated, i.e. 2.03% of cases and decreased in 6.10% of subjects. Conclusions: A hormonal disturbance was observed in almost half of the infertile men. It concerned the hypothalamus-pituitary and the testes axis and indicated mainly a state of hypogonadism with high FSH and low LH.

关 键 词：Male infertility HORMONES TESTOSTERONE FSH LH HYPOGONADISM 

分 类 号：R71[医药卫生—妇产科学]