Clinical Case: About a Probable Case of Post-Transfusion Purpura in a Homozygous Sickle Cell  

作　　者：Rakotoniaina Andriamiarimbol Irène Fenomama Jocia Fenomanana Maminirina Sonia Buscotin Eugenie Rasamindrakotroka Andry Rakoto Alson Olivat Aimé 

机构地区：[1]Laboratory Department, University Hospital Mitsinjo Betanimena, Tuléar, Madagascar [2]Laboratory Department, University Hospital Tambohobe, Fianarantsoa, Madagascar [3]Maternity Department, University Hospital Tanambao, Tuléar, Madagascar [4]Pediatric Department, University Hospital Tanambao, Tuléar, Madagascar [5]Laboratory of Immunology Department, University Hospital HJRA, Antananarivo, Madagascar [6]Laboratory of Hematology Department, University Hospital HJRA, Antananarivo, Madagascar

出　　处：《Case Reports in Clinical Medicine》2017年第6期196-199,共4页临床医学病理报告（英文）

摘　　要：Alloimmunization to platelet antigens exposes to a serious immunological incident. We report a probable case of a post-transfusion purpura from homozygous sickle cell child alloimmunized against platelet antigen. We detail the challenges of alloantibody identification and transfusion management. These challenges are due to the lack of laboratory techniques for typing HLA and HPA system and the use of leukocyte-depleted (filtered) blood products.Alloimmunization to platelet antigens exposes to a serious immunological incident. We report a probable case of a post-transfusion purpura from homozygous sickle cell child alloimmunized against platelet antigen. We detail the challenges of alloantibody identification and transfusion management. These challenges are due to the lack of laboratory techniques for typing HLA and HPA system and the use of leukocyte-depleted (filtered) blood products.

关 键 词：Post TRANSFUSION PURPURA THROMBOCYTOPENIA SICKLE Cell Disease Bumps 

分 类 号：R5[医药卫生—内科学]