A Bronchopulmonary Onset of Candidemia Revealing a Granulomatosis with Polyangiitis  

作　　者：Chaïmaâ Zeroual Mina Moudatir Khadija Echchilali Leila Barakat Hassan El Kabli Chaïmaâ Zeroual;Mina Moudatir;Khadija Echchilali;Leila Barakat;Hassan El Kabli(Department of Internal Medicine, Ibn Rochd University Hospital Center, Casablanca, Morocco)

机构地区：[1]Department of Internal Medicine, Ibn Rochd University Hospital Center, Casablanca, Morocco

出　　处：《Case Reports in Clinical Medicine》2024年第5期147-154,共8页临床医学病理报告（英文）

摘　　要：Candidemia is defined as being a yeast infection confirmed by the presence of at least one positive Candida blood culture. It is a life threatening infection causing high mortality. The clinical signs are generally compatible with the causative agent (whether there is a deep venous catheter or not). On the other hand and according to the 2012 Revised Chapel Hill Classification, granulomatosis with polyangiitis GPA is classified as a vasculitis associated with antineutrophil cytoplasmic antibodies ANCA. It is a systemic disease characterized by the anatomopathological aspect of granuloma. We report the case of a patient who presented an atypical and a very rare revealing mode of GPA which was a bronchopulmonary candidiasis complicated by candidemia. Despite its controversy, the combination in the acute phase of antifungal treatment based on intravenous voriconazole and glucocorticoid therapy has made it possible to control candidemia and calm vasculitis.Candidemia is defined as being a yeast infection confirmed by the presence of at least one positive Candida blood culture. It is a life threatening infection causing high mortality. The clinical signs are generally compatible with the causative agent (whether there is a deep venous catheter or not). On the other hand and according to the 2012 Revised Chapel Hill Classification, granulomatosis with polyangiitis GPA is classified as a vasculitis associated with antineutrophil cytoplasmic antibodies ANCA. It is a systemic disease characterized by the anatomopathological aspect of granuloma. We report the case of a patient who presented an atypical and a very rare revealing mode of GPA which was a bronchopulmonary candidiasis complicated by candidemia. Despite its controversy, the combination in the acute phase of antifungal treatment based on intravenous voriconazole and glucocorticoid therapy has made it possible to control candidemia and calm vasculitis.

关 键 词：CANDIDEMIA C. glabrata Pulmonary Candidiasis VASCULITIS IMMUNODEPRESSION Granulomatosis with Polyangiitis Cavitary Lesions Antifungal Therapy IMMUNOSUPPRESSANTS 

分 类 号：R97[医药卫生—药品]